My area of academic pursuit is the treatment of hematologic malignancies and hematopoietic stem cell transplantation. I serve as the principal investigator on several institutional clinical trials looking at strategies to improve the outcome of patients with multiple myeloma, myelodysplastic syndrome and acute leukemia. I am the institutional principal investigator for the national Cancer and Leukemia Group-B (CALGB) trials in stem cell transplantation at Washington University, and I serve on the Core Transplant Committee of the CALGB and the guidelines committees of the National Comprehensive Cancer Network (NCCN).
As the principal investigator of the Multiple Myeloma Tissue Banking initiative, I am collaborating with basic scientists in our division and the Washington University Genome Sequencing Center (GSC), one of the two largest genome sequencing centers in the world, to identify key genetic events involved in the pathogenesis of the disease and to define novel targets for drug development in multiple myeloma. I also serve on the Project Review and Steering Committees of the Multiple Myeloma Research Consortium (MMRC), an organization comprising 15 leading academic centers in the United States conducting and co-ordinating research efforts in genomics, target validation and clinical trials in multiple myeloma.
| 1989 | MBBS, Maulana Azad Medical College, University of Delhi, New Delhi, India |
| 1990 | Rotating Internship, Lok Nayak Jayaprakash Narayan & G.B. Pant Hospitals, New Delhi, India |
| 1992-1993 | Senior House Officer, Halifax General Hospital and Royal Infirmary, Halifax, West Yorkshire, UK |
| 1993-1996 | Residency, Internal Medicine, Rush Presbyterian St. Luke's Medical Center, Chicago, IL |
| 1996-1999 | Fellowship, Medical Oncology/Hematology, Washington University, St. Louis, MO |
| 1999-2000 | Fellowship, Bone Marrow Transplantation//Malignant Hematology/Stem Cell Biology, Washington University, St. Louis, MO |
| 2000-2004 | Instructor of Medicine, Section of Bone Marrow Transplantation & Leukemia, Washington University School of Medicine, St. Louis, MO |
| 2001-2004 | Staff Physician, Section of Hematology/Oncology, John Cochran VA Medical Center, St. Louis, MO |
| 2004-2007 | Assistant Professor of Medicine, Section of Bone Marrow Transplantation & Leukemia, Washington University School of Medicine, St. Louis, MO |
| 2007-present | Associate Professor of Medicine, Section of Bone Marrow Transplantation & Leukemia, Washington University School of Medicine, St. Louis, MO |
| 1991 | PLAB, General Medical Council, UK |
| 1992 | MRCP-I, Royal College of Physicians, UK |
| 1996 | Internal medicine |
| 1999 | Oncology |
| 2000 | Hematology |
| 1998 | AACR/ASCO Clinical Cancer Research Scholar |
| 1999 | Amgen Hematology Oncology Fellowship Award |
| 2005-2008 | Listed in Best Doctors in America (Best Doctors, Inc) |
| 2007 | Teacher of the year (Hematology/Oncology Fellowship Program) |
| 2008 | Honoree, Multiple Myeloma Laugh for Life (MMRF) |
| 2008 | Honoree, CUREiosity (Siteman Cancer Center Charity Gala) |
| American Society of Clinical Oncology
2009 Reviewer for Education Book (Multiple Myeloma) 2009 Chair, Myeloma Session |
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| American Society of Hematology
2006 Abstract Reviewer (Allogeneic Transplantation) 2006 Chair, Allogeneic Transplant Session 2009 Abstract Review Committee (Multiple Myeloma) |
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| St. Louis Society of Clinical Oncology | |
| American Association for the Advancement of Science |
| 2006-present | CALGB Core Transplant Committee |
| 2006-present | Multiple Myeloma Research Consortium (MMRC) Project Review Committee |
| 2006-present | NCCN Anemia Guidelines Committee |
| 2006 | Missouri State Transplant Advisory Committee |
| 2008-present | Leukemia Lymphoma Society: Patient Services Professional Resource Board |
| 2005-2006 | MDS Treatment Resource Center, NMCR |
| 2008-present | Safety Oversight group: Carfilzomib-003 study (Proteolix) |
| 2009-present | DSMB: Bortezomib+ Vorinostat trials (Merck) |
| 2002-2005 | Protocol Review and Monitoring Committee, Siteman Cancer Center |
| 2004-2005 | Transfusion Committee, Barnes-Jewish Hospital |
| 2002-2004 | Performance Improvement Committee, John Cochran VA Medical Center |
| 2007-present | Washington University Heme-Onc Fellowship Committee |