Faculty
Milan G. Chheda.jpg

Milan G. Chheda, MD

Assistant Professor
Department of Medicine
Oncology Division
Molecular Oncology
Department of Neurology

Research Interests

  • Epigenetics
  • Cancer genomics
  • Cancer stem cells
  • Glioma

Contact

  • 314-362-2877 (tel)
  • 314-362-7086 (fax)
  • Room 7609 BJC Institute of Health (office)
  • Division of Oncology
    Campus Box 8069
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Milan Chheda lab

Peer-reviewed Manuscripts

  • Zika Virus Has Oncolytic Activity Against Glioblastoma Stem Cells
    Zhu Z, Gorman MJ, McKenzie LD, Chai JN, Hubert CG, Prager BC, Fernandez E, Richner JM, Zhang R, Shan C, Wang X, Shi PY, Diamond MS, Rich JN, Chheda MG
    J Exp Med 2017 Sep 5; [Epub ahead of print]
  • Using Epigenetic Reprogramming to Treat Pediatric Brain Cancer
    Chheda MG, Gutmann DH
    Cancer Cell 2017 May 8;31(5):609-611
  • Impact of Concurrent Chemotherapy With Radiation Therapy for Elderly Patients With Newly Diagnosed Glioblastoma: A Review of the National Cancer Data Base
    Huang J, Samson P, Perkins SM, Ansstas G, Chheda MG, DeWees TA, Tsien CI, Robinson CG, Campian JL
    J Neurooncol 2017 Feb;131(3):593-601
  • Effect of Single-Agent Concurrent Chemotherapy on Survival in Anaplastic Oligodendroglioma: A Review of the National Cancer Data Base
    Acharya S, Perkins SM, Campian J, Ansstas G, Chheda M, Tsien CI, Robinson CG, Huang J
    Int J Radiat Oncol Biol Phys 2016 Oct 1;96(2S):E76-E77
  • Vandetanib Plus Sirolimus in Adults With Recurrent Glioblastoma: Results of a Phase I and Dose Expansion Cohort Study
    Chheda MG, Wen PY, Hochberg FH, Chi AS, Drappatz J, Eichler AF, Yang D, Beroukhim R, Norden AD, Gerstner ER, Betensky RA, Batchelor TT
    J Neurooncol 2015 Feb;121(3):627-34
  • ZFHX4 Interacts With the NuRD Core Member CHD4 and Regulates the Glioblastoma Tumor-Initiating Cell State
    Chudnovsky Y, Kim D, Zheng S, Whyte WA, Bansal M, Bray MA, Gopal S, Theisen MA, Bilodeau S, Thiru P, Muffat J, Yilmaz OH, Mitalipova M, Woolard K, Lee J, Nishimura R, Sakata N, Fine HA, Carpenter AE, Silver SJ, Verhaak RG, Califano A, Young RA, Ligon KL, Mellinghoff IK, Root DE, Sabatini DM, Hahn WC, Chheda MG
    Cell Rep 2014 Jan 30;6(2):313-24
  • Integrative Functional Genomics Identifies RINT1 as a Novel GBM Oncogene
    Quayle SN, Chheda MG, Shukla SA, Wiedemeyer R, Tamayo P, Dewan RW, Zhuang L, Huang-Hobbs E, Haidar S, Xiao Y, Ligon KL, Hahn WC, Chin L
    Neuro Oncol 2012 Nov;14(11):1325-31
  • Differential Sensitivity of Glioma- Versus Lung Cancer-Specific EGFR Mutations to EGFR Kinase Inhibitors
    Vivanco I, Robins HI, Rohle D, Campos C, Grommes C, Nghiemphu PL, Kubek S, Oldrini B, Chheda MG, Yannuzzi N, Tao H, Zhu S, Iwanami A, Kuga D, Dang J, Pedraza A, Brennan CW, Heguy A, Liau LM, Lieberman F, Yung WK, Gilbert MR, Reardon DA, Drappatz J, Wen PY, Lamborn KR, Chang SM, Prados MD, Fine HA, Horvath S, Wu N, Lassman AB, DeAngelis LM, Yong WH, Kuhn JG, Mischel PS, Mehta MP, Cloughesy TF, Mellinghoff IK
    Cancer Discov 2012 May;2(5):458-71
  • Pattern of Retinoblastoma Pathway Inactivation Dictates Response to CDK4/6 Inhibition in GBM
    Wiedemeyer WR, Dunn IF, Quayle SN, Zhang J, Chheda MG, Dunn GP, Zhuang L, Rosenbluh J, Chen S, Xiao Y, Shapiro GI, Hahn WC, Chin L
    Proc Natl Acad Sci U S A 2010 Jun 22;107(25):11501-6
  • PLAGL2 Regulates Wnt Signaling to Impede Differentiation in Neural Stem Cells and Gliomas
    Zheng H, Ying H, Wiedemeyer R, Yan H, Quayle SN, Ivanova EV, Paik JH, Zhang H, Xiao Y, Perry SR, Hu J, Vinjamoori A, Gan B, Sahin E, Chheda MG, Brennan C, Wang YA, Hahn WC, Chin L, DePinho RA
    Cancer Cell 2010 May 18;17(5):497-509
  • CDK8 Is a Colorectal Cancer Oncogene That Regulates Beta-Catenin Activity
    Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC
    Nature 2008 Sep 25;455(7212):547-51
  • Hepatitis B Reactivation During Glioblastoma Treatment With Temozolomide: A Cautionary Note
    Chheda MG, Drappatz J, Greenberger NJ, Kesari S, Weiss SE, Gigas DC, Doherty LM, Wen PY
    Neurology 2007 Mar 20;68(12):955-6
  • Two NOTCH4 Polymorphisms and Their Relation to Schizophrenia Susceptibility and Different Personality Traits
    Carmine A, Chheda MG, Jonsson EG, Sedvall GC, Farde L, Gustavsson JP, Bergman H, Anvret M, Buervenich S, Olson L
    Psychiatr Genet 2003 Mar;13(1):23-8
  • Phosphorylation of Snapin by PKA Modulates Its Interaction With the SNARE Complex
    Chheda MG, Ashery U, Thakur P, Rettig J, Sheng ZH
    Nat Cell Biol 2001 Apr;3(4):331-8