Faculty
Todd Fehniger.jpg

Todd A. Fehniger, MD, PhD

Associate Professor
Department of Medicine
Oncology Division
Stem Cell Biology
Bone Marrow Transplantation & Leukemia

Clinical Interests

  • Lymphoma
  • Leukemia
  • Immunotherapy
  • Hematopoietic cell transplantation

Research Interests

  • Innate immunity
  • Natural killer cell biology
  • Micro RNAs
  • Cytokines
  • Natural killer cell based therapeutics

Contact

  • 314-747-1547 (lab)
  • 314-747-1385 (lab office)
  • 314-362-9333 (fax)
  • 6th Floor Southwest Tower, Room 638 (office)
  • 6th Floor Southwest Tower, Room 634 (lab)
  • Division of Oncology
    Section of Stem Cell Biology
    Campus Box 8007
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Fehniger Laboratory

Invited Publications & Book Chapters

  • Harnessing NK cell memory for cancer immunotherapy
    Fehniger TA, Cooper MA
    Trends Immunol 2016 Oct 20; [Epub ahead of print]
  • Human adaptive natural killer cells: beyond NKG2C
    Wagner JA, Fehniger TA
    Trends Immunol 2016 Jun;37(6):351-3
  • Memory NK cells take out the (mitochondrial) garbage
    Wagner JA, Fehniger TA
    Immunity 2015 Aug 18;43(2):218-20
  • Chapter 28. Hematologic malignancies: chronic leukemias
    Romee R, Fehniger TA
    In: The Washington Manual of Oncology, 3rd Edition (Govindan R, ed), Lippincott, Williams, and Wilkins, Philadelphia, PA, 2007
  • Extracellular microRNAs turn on NK cells via TLR1
    Fehniger TA
    Blood 2013 Jun 6;121(23):4612-3
  • "AbroGATAed" human NK cell development
    Fehniger TA
    Blood 2013 Apr 4;121(14):2579-80
  • Unraveling the molecular events leading to the genesis of large granular lymphocytic leukemia reveals a new treatment strategy
    Fehniger TA
    Haematologica 2013 Feb;98(2):159
  • Human NK cells: SET to kill
    Leong JW, Fehniger TA
    Blood 2011 Feb 24;117(8):2297-8
  • Chapter 31. Lymphoma
    Fehniger TA
    In: The Washington Manual, Hematology and Oncology Subspecialty Consult, 2nd Edition (Cashen AF, Wildes T, eds), Lippincott, Williams, and Wilkins, Philadelphia, PA, 2008
  • Chapter 28. Hematologic malignancies: chronic leukemias
    Fehniger TA, Welch JS, Pluard TJ
    In: The Washington Manual of Oncology, 2nd Edition (Govindan R, ed), Lippincott, Williams, and Wilkins, Philadelphia, PA, 2007
  • Chapter 12. Murine cytokine models and the genesis of cancer
    Fehniger TA, Cooper MA, Caligiuri MA
    In: Cytokines in the genesis and treatment of cancer (Caligiuri MA, Lotze MT, eds), Humana Press, Totowa, NJ, 2007
  • Orphan granzyme turned lethal weapon (Inside Blood)
    Fehniger TA
    Blood 110:475-476, 2007
  • NK cell and DC interactions
    Cooper MA, Fehniger TA, Fuchs A, Colonna M, Caligiuri MA
    Trends Immunol 2004 Jan;25(1):47-52
  • Biology and clinical impact of human natural killer cells
    Farag SS, VanDeusen JB, Fehniger TA, Caligiuri MA
    Int J Hematol 2003 Jul;78(1):7-17
  • New directions in natural killer cell-based immunotherapy of human cancer
    Farag SS, Fehniger TA, Becknell B, Blaser BW, Caligiuri MA
    Expert Opin Biol Ther 2003 Apr;3(2):237-50
  • Natural killer cells: biology and application in stem-cell transplantation
    Farag SS, Fehniger T, Ruggeri L, Velardi A, Caligiuri MA
    Cytotherapy 2002;4(5):445-6
  • Interleukin-2 and interleukin-15: immunotherapy for cancer
    Fehniger TA, Cooper MA, Caligiuri MA
    Cytokine Growth Factor Rev 2002 Apr;13(2):169-83
  • Ontogeny and expansion of human natural killer cells: clinical implications
    Fehniger TA, Caligiuri MA
    Int Rev Immunol 2001 Jun;20(3-4):503-34
  • Fatal leukemia in interleukin-15 transgenic mice
    Fehniger TA, Suzuki K, VanDeusen JB, Cooper MA, Freud AG, Caligiuri MA
    Blood Cells Mol Dis 2001 Jan-Feb;27(1):223-30
  • Cytokine replacement in patients with HIV-1 non-Hodgkin's lymphoma: the rationale for low-dose interleukin-2 therapy
    Shah MH, Baiocchi RA, Fehniger TA, Khatri VP, Gould M, Poiesz B, Bernstein ZP, Caligiuri MA
    Cancer J Sci Am 2000 Feb;6 Suppl 1:S45-51
  • Costimulation of human natural killer cells is required for interferon gamma production
    Fehniger TA, Carson WE, Caligiuri MA
    Transplant Proc 1999 May;31(3):1476-8