Faculty
Chris Sturgeon.jpg

Christopher M. Sturgeon, PhD

Assistant Professor
Department of Medicine
Hematology Division
Department of Developmental Biology

Research Interests

  • Embryonic stem cells
  • Pluripotent stem cells
  • Hematopoiesis
  • Developmental Biology

Contact

  • 314-362-8893 (office)
  • 314-362-8826 (fax)
  • Room 8868 Clinical Sciences Research Building (lab)
  • Hematology Division
    Campus Box 8125
    Washington University School of Medicine
    660 South Euclid Avenue
    St. Louis, MO 63110

Peer-reviewed Manuscripts

  • p53 Mediates Failure of Human Definitive Hematopoiesis in Dyskeratosis Congenita
    Fok WC, Niero ELO, Dege C, Brenner KA, Sturgeon CM, Batista LFZ
    Stem Cell Reports 2017 Aug 8;9(2):409-418
  • Human Definitive Hematopoietic Specification From Pluripotent Stem Cells Is Regulated by Mesodermal Expression of CDX4
    Creamer JP, Dege C, Ren Q, Ho JTK, Valentine MC, Druley TE, Sturgeon CM
    Blood 2017 Jun 1;129(22):2988-2992
  • Directed Differentiation of Definitive Hemogenic Endothelium and Hematopoietic Progenitors From Human Pluripotent Stem Cells
    Ditadi A, Sturgeon CM
    Methods 2016 May 15;101:65-72
  • Human Definitive Haemogenic Endothelium and Arterial Vascular Endothelium Represent Distinct Lineages
    Ditadi A, Sturgeon CM, Tober J, Awong G, Kennedy M, Yzaguirre AD, Azzola L, Ng ES, Stanley EG, French DL, Cheng X, Gadue P, Speck NA, Elefanty AG, Keller G
    Nat Cell Biol 2015 May;17(5):580-91
  • Wnt Signaling Controls the Specification of Definitive and Primitive Hematopoiesis From Human Pluripotent Stem Cells
    Sturgeon CM, Ditadi A, Awong G, Kennedy M, Keller G
    Nat Biotechnol 2014 Jun;32(6):554-61
  • T Lymphocyte Potential Marks the Emergence of Definitive Hematopoietic Progenitors in Human Pluripotent Stem Cell Differentiation Cultures
    Kennedy M, Awong G, Sturgeon CM, Ditadi A, LaMotte-Mohs R, Zuniga-Pflucker JC, Keller G
    Cell Rep 2012 Dec 27;2(6):1722-35
  • Primitive Erythropoiesis Is Regulated by miR-126 Via Nonhematopoietic Vcam-1+ Cells
    Sturgeon CM, Chicha L, Ditadi A, Zhou Q, McGrath KE, Palis J, Hammond SM, Wang S, Olson EN, Keller G
    Dev Cell 2012 Jul 17;23(1):45-57
  • Abrogation of Ionizing Radiation-Induced G2 Checkpoint and Inhibition of Nuclear Export by Cryptocarya Pyrones
    Sturgeon CM, Cinel B, Diaz-Marrero AR, McHardy LM, Ngo M, Andersen RJ, Roberge M
    Cancer Chemother Pharmacol 2008 Mar;61(3):407-13
  • Nigricanosides A and B, Antimitotic Glycolipids Isolated From the Green Alga Avrainvillea Nigricans Collected in Dominica
    Williams DE, Sturgeon CM, Roberge M, Andersen RJ
    J Am Chem Soc 2007 May 9;129(18):5822-3
  • G2 Checkpoint Kinase Inhibitors Exert Their Radiosensitizing Effects Prior to the G2/M Transition
    Sturgeon CM, Roberge M
    Cell Cycle 2007 Mar 1;6(5):572-5
  • Inhibition of the G2 DNA Damage Checkpoint by Oliveroline Isolated From Duguetia Odorata
    Brastianos HC, Sturgeon CM, Roberge M, Andersen RJ
    J Nat Prod 2007 Feb;70(2):287-8
  • Effect of Combined DNA Repair Inhibition and G2 Checkpoint Inhibition on Cell Cycle Progression After DNA Damage
    Sturgeon CM, Knight ZA, Shokat KM, Roberge M
    Mol Cancer Ther 2006 Apr;5(4):885-92
  • Modulation of the G2 Cell Cycle Checkpoint by Sesquiterpene Lactones Psilostachyins A and C Isolated From the Common Ragweed Ambrosia Artemisiifolia
    Sturgeon CM, Craig K, Brown C, Rundle NT, Andersen RJ, Roberge M
    Planta Med 2005 Oct;71(10):938-43
  • Freeze-Induced Expression of a Novel Gene, Fr47, in the Liver of the Freeze-Tolerant Wood Frog, Rana Sylvatica
    McNally JD, Sturgeon CM, Storey KB
    Biochim Biophys Acta 2003 Jan 27;1625(2):183-91
  • Identification and Characterization of a Novel Freezing Inducible Gene, Li16, in the Wood Frog Rana Sylvatica
    McNally JD, Wu SB, Sturgeon CM, Storey KB
    FASEB J 2002 Jun;16(8):902-4