Jian Li Campian.jpg

Jian Li Campian, MD, PhD

Assistant Professor
Department of Medicine
Oncology Division
Medical Oncology
Department of Neurological Surgery

Clinical Interests

  • Brain tumors

Research Interests

  • Neuro-oncology:
  • - Immunotherapy
  • - Target therapy
  • - Early phase clinic trial development


  • 314-362-5677 (tel)
  • 314-362-7086 (fax)
  • 11th Floor Mid-Campus Center (office)
  • Division of Oncology
    Campus Box 8056
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110


  • Effect of Radiation Treatment Volume Reduction on Lymphopenia in Patients Receiving Chemoradiotherapy for Glioblastoma
    Rudra S, Hui C, Rao YJ, Samson P, Lin AJ, Chang X, Tsien C, Fergus S, Mullen D, Yang D, Thotala D, Hallahan D, Campian JL, Huang J
    Int J Radiat Oncol Biol Phys 2018 Feb 1; [Epub ahead of print]
  • Final Results of a Phase I Dose-Escalation, Dose-Expansion Study of Adding Disulfiram With or Without Copper to Adjuvant Temozolomide for Newly Diagnosed Glioblastoma
    Huang J, Campian JL, Gujar AD, Tsien C, Ansstas G, Tran DD, DeWees TA, Lockhart AC, Kim AH
    J Neurooncol 2018 Jan 27; [Epub ahead of print]
  • Biological and Therapeutic Implications of Multisector Sequencing in Newly Diagnosed Glioblastomas
    Mahlokozera T, Vellimana AK, Li T, Mao DD, Zohny ZS, Kim DH, Tran DD, Marcus DS, Fouke SJ, Campian JL, Dunn GP, Miller CA, Kim AH
    Neuro Oncol 2017 Dec 13; [Epub ahead of print]
  • Serial Changes in Lymphocyte Subsets in Patients With Newly Diagnosed High Grade Astrocytomas Treated With Standard Radiation and Temozolomide
    Campian JL, Piotrowski AF, Ye X, Hakim FT, Rose J, Yan XY, Lu Y, Gress R, Grossman SA
    J Neurooncol 2017 Nov;135(2):343-351
  • Rindopepimut With Temozolomide for Patients With Newly Diagnosed, EGFRvIII-Expressing Glioblastoma (ACT IV): A Randomised, Double-Blind, International Phase 3 Trial
    Weller M, Butowski N, Tran DD, Recht LD, Lim M, Hirte H, Ashby L, Mechtler L, Goldlust SA, Iwamoto F, Drappatz J, O'Rourke DM, Wong M, Hamilton MG, Finocchiaro G, Perry J, Wick W, Green J, He Y, Turner CD, Yellin MJ, Keler T, Davis TA, Stupp R, Sampson JH
    ACT IV trial investigators (Contributors include: Campian J)

    Lancet Oncol 2017 Oct;18(10):1373-1385
  • Diagnostic and Therapeutic Strategies for Patients With Malignant Epidural Spinal Cord Compression
    Patel DA, Campian JL
    Curr Treat Options Oncol 2017 Aug 10;18(9):53
  • CNS Tumors in Neurofibromatosis
    Campian J, Gutmann DH
    J Clin Oncol 2017 Jul 20;35(21):2378-2385
  • Impact of Concurrent Chemotherapy With Radiation Therapy for Elderly Patients With Newly Diagnosed Glioblastoma: A Review of the National Cancer Data Base
    Huang J, Samson P, Perkins SM, Ansstas G, Chheda MG, DeWees TA, Tsien CI, Robinson CG, Campian JL
    J Neurooncol 2017 Feb;131(3):593-601
  • Imaging Changes Following Proton Radiation Therapy in Adult Diffuse Gliomas
    Meeks M, Acharya S, Huang J, Robinson CG, Perkins SM, Campian J, Ansstas G, Kim A, Dunn G, Zhao T, Sun B, Rich K, Tsien CI
    Int J Radiat Oncol Biol Phys 2016 Oct 1;96(2S):E106
  • Effect of Single-Agent Concurrent Chemotherapy on Survival in Anaplastic Oligodendroglioma: A Review of the National Cancer Data Base
    Acharya S, Perkins SM, Campian J, Ansstas G, Chheda M, Tsien CI, Robinson CG, Huang J
    Int J Radiat Oncol Biol Phys 2016 Oct 1;96(2S):E76-E77
  • Association Between Treatment-Related Lymphopenia and Overall Survival in Elderly Patients With Newly Diagnosed Glioblastoma
    Mendez JS, Govindan A, Leong J, Gao F, Huang J, Campian JL
    J Neurooncol 2016 Apr;127(2):329-35
  • A Phase I Study to Repurpose Disulfiram in Combination With Temozolomide to Treat Newly Diagnosed Glioblastoma After Chemoradiotherapy
    Huang J, Campian JL, Gujar AD, Tran DD, Lockhart AC, DeWees TA, Tsien CI, Kim AH
    J Neurooncol 2016 Jun;128(2):259-66
  • Hyperthermic Laser Ablation of Recurrent Glioblastoma Leads to Temporary Disruption of the Peritumoral Blood Brain Barrier
    Leuthardt EC, Duan C, Kim MJ, Campian JL, Kim AH, Miller-Thomas MM, Shimony JS, Tran DD
    PLoS One 2016 Feb 24;11(2):e0148613
  • Pre-Radiation Lymphocyte Harvesting and Post-Radiation Reinfusion in Patients With Newly Diagnosed High Grade Gliomas
    Campian JL, Ye X, Gladstone DE, Ambady P, Nirschl TR, Borrello I, Golightly M, King KE, Holdhoff M, Karp J, Drake CG, Grossman SA
    J Neurooncol 2015 Sep;124(2):307-16
  • Survival in Patients With Severe Lymphopenia Following Treatment With Radiation and Chemotherapy for Newly Diagnosed Solid Tumors
    Grossman SA, Ellsworth S, Campian J, Wild AT, Herman JM, Laheru D, Brock M, Balmanoukian A, Ye X
    J Natl Compr Canc Netw 2015 Oct;13(10):1225-31
  • Stem Cell Transfusion Restores Immune Function in Radiation-Induced Lymphopenic C57BL/6 Mice
    Kapoor V, Khudanyan A, de la Puente P, Campian J, Hallahan DE, Azab AK, Thotala D
    Cancer Res 2015 Sep 1;75(17):3442-5
  • Clinical and Dosimetric Predictors of Acute Severe Lymphopenia During Radiation Therapy and Concurrent Temozolomide for High-Grade Glioma
    Huang J, DeWees TA, Badiyan SN, Speirs CK, Mullen DF, Fergus S, Tran DD, Linette G, Campian JL, Chicoine MR, Kim AH, Dunn G, Simpson JR, Robinson CG
    Int J Radiat Oncol Biol Phys 2015 Aug 1;92(5):1000-7
  • The Association Between Chemoradiation-Related Lymphopenia and Clinical Outcomes in Patients With Locally Advanced Pancreatic Adenocarcinoma
    Wild AT, Ye X, Ellsworth SG, Smith JA, Narang AK, Garg T, Campian J, Laheru DA, Zheng L, Wolfgang CL, Tran PT, Grossman SA, Herman JM
    Am J Clin Oncol 2015 Jun;38(3):259-265
  • Infusion of Cryopreserved Autologous Lymphocytes Using a Standard Peripheral I.V. Catheter
    Gladstone DE, Davis-Sproul J, Campian J, Lemas MV, Malatyali S, Borrello I, King K, Grossman SA
    Bone Marrow Transplant 2014 Aug;49(8):1119-20
  • Association Between Severe Treatment-Related Lymphopenia and Progression-Free Survival in Patients With Newly Diagnosed Squamous Cell Head and Neck Cancer
    Campian JL, Sarai G, Ye X, Marur S, Grossman SA
    Head Neck 2014 Dec;36(12):1747-53
  • Treatment-Related Lymphopenia in Patients With Stage III Non-Small-Cell Lung Cancer
    Campian JL, Ye X, Brock M, Grossman SA
    Cancer Invest 2013 Mar;31(3):183-8
  • Mitochondrial Dysfunction May Explain the Cardiomyopathy of Chronic Iron Overload
    Gao X, Qian M, Campian JL, Marshall J, Zhou Z, Roberts AM, Kang YJ, Prabhu SD, Sun XF, Eaton JW
    Free Radic Biol Med 2010 Aug 1;49(3):401-7
  • Management of Chronic Lymphocytic Leukemia: An Update
    Kaufman M, Campian JL, Rai KR
    Community Oncology 2009;6:271-8
  • Mitochondrial DNA Damage in Iron Overload
    Gao X, Campian JL, Qian M, Sun XF, Eaton JW
    J Biol Chem 2009 Feb 20;284(8):4767-75
  • Generation of Oxidants by Hypoxic Human Pulmonary and Coronary Smooth-Muscle Cells
    Mehta JP, Campian JL, Guardiola J, Cabrera JA, Weir EK, Eaton JW
    Chest 2008 Jun;133(6):1410-4
  • Cytochrome C Oxidase Activity and Oxygen Tolerance
    Campian JL, Gao X, Qian M, Eaton JW
    J Biol Chem 2007 Apr 27;282(17):12430-8
  • Cytotoxic and Mutagenic Effects of Tobacco-Borne Free Fatty Acids
    Gao X, Qian M, Campian JL, Clark DR, Burke TJ, Eaton JW, McGregor WG
    Free Radic Biol Med 2006 Jan 1;40(1):165-72
  • Oxygen Tolerance and Coupling of Mitochondrial Electron Transport
    Campian JL, Qian M, Gao X, Eaton JW
    J Biol Chem 2004 Nov 5;279(45):46580-7
  • Mitochondrial Metabolism Underlies Hyperoxic Cell Damage
    Li J, Gao X, Qian M, Eaton JW
    Free Radic Biol Med 2004 Jun 1;36(11):1460-70
  • Oxygen Toxicity and Mitochondrial Metabolism
    Li J
    PhD Dissertation, University of Louisville, 2003
  • Mitochondrial Metabolism and Oxygen Toxicity
    Li J
    MS Thesis, University of Louisville, 2002
  • The Regulatory Effects of TNF-Alpha, Angiotensin-II and MmLDL on PDGF-B Chain Gene Transcription in Vascular Endothelial Cells
    Li J
    MS Thesis, Peking Union Medical College, 2000