Faculty
Oncology Division
Eades.jpg

William C. Eades, Jr.

Associate Professor
Department of Medicine
Oncology Division
Stem Cell Biology

Research Interests

  • Isolation techniques for background autofluorescence
  • Extreme wavelength laser integration to flow cytometry (<350nm and >750nm)
  • Carbon based semiconductor dye conjugate development

Contact

  • 314-362-9364 (tel)
  • 314-362-4298 (fax)
  • 702A Southwest Tower (office)
    702-704 Southwest Tower (lab)
  • Division of Oncology
    Campus Box 8007
    Washington University Medical Center
    660 South Euclid Avenue
    St. Louis, MO 63110
  • Siteman Flow Cytometry Core

Publications

  • OMIP-042: 21-Color Flow Cytometry to Comprehensively Immunophenotype Major Lymphocyte and Myeloid Subsets in Human Peripheral Blood
    Staser KW, Eades W, Choi J, Karpova D, DiPersio JF
    Cytometry A 2018 Feb;93(2):186-189
  • Cell-Free Measurements of Brightness of Fluorescently Labeled Antibodies
    Zhou H, Tourkakis G, Shi D, Kim DM, Zhang H, Du T, Eades WC, Berezin MY
    Sci Rep 2017 Feb 2;7:41819
  • A Phase 1/2 Study of Chemosensitization With Plerixafor Plus G-CSF in Relapsed or Refractory Acute Myeloid Leukemia
    Uy GL, Rettig MP, Stone RM, Konopleva MY, Andreeff M, McFarland K, Shannon W, Fletcher TR, Reineck T, Eades W, Stockerl-Goldstein K, Abboud CN, Jacoby MA, Westervelt P, DiPersio JF
    Blood Cancer J 2017 Mar 10;7(3):e542
  • Mobilization of Allogeneic Peripheral Blood Stem Cell Donors With Intravenous Plerixafor Mobilizes a Unique Graft
    Schroeder MA, Rettig MP, Lopez S, Christ S, Fiala M, Eades W, Mir FA, Shao J, McFarland K, Trinkaus K, Shannon W, Deych E, Yu J, Vij R, Stockerl-Goldstein K, Cashen AF, Uy GL, Abboud CN, Westervelt P, DiPersio JF
    Blood 2017 May 11;129(19):2680-2692
  • Targeting CD123 in Acute Myeloid Leukemia Using a T-Cell-Directed Dual-Affinity Retargeting Platform
    Al-Hussaini M, Rettig MP, Ritchey JK, Karpova D, Uy GL, Eissenberg LG, Gao F, Eades WC, Bonvini E, Chichili GR, Moore PA, Johnson S, Collins L, DiPersio JF
    Blood 2016 Jan 7;127(1):122-31
  • Visualization of Pulmonary Clearance Mechanisms Via Noninvasive Optical Imaging Validated by Near-Infrared Flow Cytometry
    Zhou H, Gunsten SP, Zhegalova NG, Bloch S, Achilefu S, Christopher Holley J, Schweppe D, Akers W, Brody SL, Eades WC, Berezin MY
    Cytometry A 2015;87(5):419-27
  • Proteopathic Tau Seeding Predicts Tauopathy in Vivo
    Holmes BB, Furman JL, Mahan TE, Yamasaki TR, Mirbaha H, Eades WC, Belaygorod L, Cairns NJ, Holtzman DM, Diamond MI
    Proc Natl Acad Sci U S A 2014 Oct 14;111(41):E4376-85
  • Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing
    Hughes AE, Magrini V, Demeter R, Miller CA, Fulton R, Fulton LL, Eades WC, Elliott K, Heath S, Westervelt P, Ding L, Conrad DF, White BS, Shao J, Link DC, DiPersio JF, Mardis ER, Wilson RK, Ley TJ, Walter MJ, Graubert TA
    PLoS Genet 2014 Jul 10;10(7):e1004462
  • Functional Heterogeneity of Genetically Defined Subclones in Acute Myeloid Leukemia
    Klco JM, Spencer DH, Miller CA, Griffith M, Lamprecht TL, O'Laughlin M, Fronick C, Magrini V, Demeter RT, Fulton RS, Eades WC, Link DC, Graubert TA, Walter MJ, Mardis ER, DiPersio JF, Wilson RK, Ley TJ
    Cancer Cell 2014 Mar 17;25(3):379-92
  • Clonal Architecture of Secondary Acute Myeloid Leukemia
    Walter MJ, Shen D, Ding L, Shao J, Koboldt DC, Chen K, Larson DE, McLellan MD, Dooling D, Abbott R, Fulton R, Magrini V, Schmidt H, Kalicki-Veizer J, O'Laughlin M, Fan X, Grillot M, Witowski S, Heath S, Frater JL, Eades W, Tomasson M, Westervelt P, DiPersio JF, Link DC, Mardis ER, Ley TJ, Wilson RK, Graubert TA
    N Engl J Med 2012 Mar 22;366(12):1090-8
  • Csf3r Mutations in Mice Confer a Strong Clonal HSC Advantage Via Activation of Stat5
    Liu F, Kunter G, Krem MM, Eades WC, Cain JA, Tomasson MH, Hennighausen L, Link DC
    J Clin Invest 2008 Mar;118(3):946-55
  • Widespread Nonhematopoietic Tissue Distribution by Transplanted Human Progenitor Cells With High Aldehyde Dehydrogenase Activity
    Hess DA, Craft TP, Wirthlin L, Hohm S, Zhou P, Eades WC, Creer MH, Sands MS, Nolta JA
    Stem Cells 2008 Mar;26(3):611-20
  • Systematic Analysis of the Transcriptional Switch Inducing Migration of Border Cells
    Borghese L, Fletcher G, Mathieu J, Atzberger A, Eades WC, Cagan RL, Rorth P
    Dev Cell 2006 Apr;10(4):497-508
  • Selection Based on CD133 and High Aldehyde Dehydrogenase Activity Isolates Long-Term Reconstituting Human Hematopoietic Stem Cells
    Hess DA, Wirthlin L, Craft TP, Herrbrich PE, Hohm SA, Lahey R, Eades WC, Creer MH, Nolta JA
    Blood 2006 Mar 1;107(5):2162-9
  • Gene Targeting Strategies for the Isolation of Hematopoietic and Endothelial Precursors From Differentiated ES Cells
    Zhang WJ, Chung YS, Eades B, Choi K
    Methods Enzymol 2003;365:186-202