Linda Eissenberg.jpg

Linda G. Eissenberg, PhD

Assistant Professor
Department of Medicine
Oncology Division
Stem Cell Biology

Research Interests

  • Gene therapy / suicide gene
  • Chimeric antigen receptor / bispecific targeting reagents
  • T cells
  • Leukemia / graft vs. host disease
  • Mobilization of hematopoietic stem cells
  • Chemosensitization by mobilizing leukemia cells


  • 314-362-7558 (tel)
  • 314-362-9333 (fax)
  • Room 626P Southwest Tower (lab)
  • Division of Oncology
    Campus Box 8007
    Washington University Medical School
    660 South Euclid Avenue
    St. Louis, MO 63110

Peer-reviewed Manuscripts

  • An "Off-The-Shelf" Fratricide-Resistant CAR-T for the Treatment of T Cell Hematologic Malignancies
    Cooper ML, Choi J, Staser K, Ritchey JK, Devenport JM, Eckardt K, Rettig MP, Wang B, Eissenberg LG, Ghobadi A, Gehrs LN, Prior JL, Achilefu S, Miller CA, Fronick CC, O'Neal J, Gao F, Weinstock DM, Gutierrez A, Fulton RS, DiPersio JF
    Leukemia 2018 Feb 20; [Epub ahead of print]
  • Enhanced in Utero Allogeneic Engraftment in Mice After Mobilizing Fetal HSCs by Alpha4beta1/7 Inhibition
    Kim AG, Vrecenak JD, Boelig MM, Eissenberg L, Rettig MP, Riley JS, Holt MS, Conner MA, Loukogeorgakis SP, Li H, DiPersio JF, Flake AW, Peranteau WH
    Blood 2016 Nov 17;128(20):2457-2461
  • Phase I Study of Azacitidine Following Donor Lymphocyte Infusion for Relapsed Acute Myeloid Leukemia Post Allogeneic Stem Cell Transplantation
    Ghobadi A, Choi J, Fiala MA, Fletcher T, Liu J, Eissenberg LG, Abboud C, Cashen A, Vij R, Schroeder MA, Pusic I, Stockerl-Goldstein K, Jacoby M, Uy G, DiPersio J, Westervelt P
    Leuk Res 2016 Oct;49:1-6
  • [(18)F]FHBG PET/CT Imaging of CD34-TK75 Transduced Donor T Cells in Relapsed Allogeneic Stem Cell Transplant Patients: Safety and Feasibility
    Eissenberg LG, Rettig MP, Ritchey JK, Prior JL, Schwarz SW, Frye J, White BS, Fulton RS, Ghobadi A, Cooper ML, Couriel DR, Seegulam ME, Piwnica-Worms D, Dehdashti F, Cornetta K, DiPersio JF
    Mol Ther 2015 Jun;23(6):1110-22
  • Bortezomib Is a Rapid Mobilizer of Hematopoietic Stem Cells in Mice Via Modulation of the VCAM-1/VLA-4 Axis
    Ghobadi A, Rettig MP, Cooper ML, Holt MS, Ritchey JK, Eissenberg L, DiPersio JF
    Blood 2014 Oct 23;124(17):2752-4
  • Histoplasma Capsulatum Alpha-(1,3)-Glucan Blocks Innate Immune Recognition by the Beta-Glucan Receptor
    Rappleye CA, Eissenberg LG, Goldman WE
    Proc Natl Acad Sci U S A 2007 Jan 23;104(4):1366-70
  • Phenotypic Variation and Intracellular Parasitism by Histoplasma Capsulatum
    Kugler S*, Schurtz-Sebghati T*, Eissenberg LG*, Goldman WE (*contributed equally)
    Proc Natl Acad Sci U S A 2000 Aug 1;97(16):8794-8
  • Alterations to the Cell Wall of Histoplasma Capsulatum Yeasts During Infection of Macrophages or Epithelial Cells
    Eissenberg LG, Moser SA, Goldman WE
    J Infect Dis 1997 Jun;175(6):1538-44
  • Phenotypic Variation and Persistence of Histoplasma Capsulatum Yeasts in Host Cells
    Eissenberg LG, Poirier S, Goldman WE
    Infect Immun 1996 Dec;64(12):5310-4
  • Histoplasma Capsulatum Modulates the Acidification of Phagolysosomes
    Eissenberg LG, Goldman WE, Schlesinger PH
    J Exp Med 1993 Jun 1;177(6):1605-11
  • Infection of P388D1 Macrophages and Respiratory Epithelial Cells by Histoplasma Capsulatum: Selection of Avirulent Variants and Their Potential Role in Persistent Histoplasmosis
    Eissenberg LG, West JL, Woods JP, Goldman WE
    Infect Immun 1991 May;59(5):1639-46
  • Phagosome-Lysosome Fusion in P388D1 Macrophages Infected With Histoplasma Capsulatum
    Eissenberg LG, Schlesinger PH, Goldman WE
    J Leukoc Biol 1988 Jun;43(6):483-91
  • Histoplasma Capsulatum Fails to Trigger Release of Superoxide From Macrophages
    Eissenberg LG, Goldman WE
    Infect Immun 1987 Jan;55(1):29-34
  • Chlamydia Psittaci Elementary Body Envelopes: Ingestion and Inhibition of Phagolysosome Fusion
    Eissenberg LG, Wyrick PB, Davis CH, Rumpp JW
    Infect Immun 1983 May;40(2):741-51
  • Inhibition of Phagolysosome Fusion Is Localized to Chlamydia Psittaci-Laden Vacuoles
    Eissenberg LG, Wyrick PB
    Infect Immun 1981 May;32(2):889-96