Faculty
Oncology Division
Obi L. Griffith, PhD
Associate Professor
Department of Medicine
Oncology Division
Stem Cell Biology
Department of Genetics
McDonnell Genome Institute
Research Interests
- Cancer informatics
- Clinical statistics
- Breast cancer
Contact
- 314-747-9248 (office)
- 314-286-1810 (fax)
- obigriffith@wustl.edu
- Division of Oncology
Mail Stop 8501-0029-10
Washington University
660 South Euclid Avenue
St. Louis, MO 63110 - Room 10116, Mid Campus Center (lab)
- Griffith Lab Website
Biosketch
| Education | |
|---|---|
| 1996-2002 | BSc in Biology (Honours) and Biochemistry, University of Winnipeg, Winnipeg, MB, Canada |
| 2003-2004 | Molecular Biology Graduate Exchange, Simon Fraser University, Burnaby, BC, Canada |
| 2003-2008 | PhD in Medical Genetics, University of British Columbia, Vancouver, BC, Canada |
| Academic Positions & Employment | |
| 2002-2003 | Computational Biologist/Sequence Finisher (Steven Jones; Marco Marra), BC Cancer Agency, Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada |
| 2008-2010 | Post-Doctoral Fellow, Medical Genetics (Steven Jones), BC Cancer Agency, Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada |
| 2010-2012 | Post-Doctoral Fellow, Cancer & DNA Damage (Joe Gray; Paul Spellman), Lawrence Berkeley National Laboratory, Berkeley, CA |
| 2011-2012 | Visiting Scientist, Molecular and Medical Genetics, Oregon Health and Science University, Portland, OR |
| 2012-2014 | Research Assistant Professor, Department of Medicine, Washington University, St. Louis, MO |
| 2012-2014 | Genome Fellow, The Genome Institute, Washington University, St. Louis, MO |
| 2014-2019 | Assistant Professor, Departments of Medicine and Genetics, Washington University, St. Louis, MO |
| 2014-present | Assistant Director, The Genome Institute, Washington University, St. Louis, MO |
| 2019-present | Associate Professor, Departments of Medicine and Genetics, Washington University, St. Louis, MO |
| University & Hospital Appointments & Committees | |
| 2014-present | Member, Division of Biology and Biomedical Sciences |
| 2014-present | Member, Siteman Cancer Center |
| 2016-present | Faculty, Clinical Informatics Fellowship Program |
| 2016-present | Faculty, Molecular Oncology Training Program |
| 2016-present | Mentor, Initiative for Maximizing Student Development Program |
| 2017-present | Member, Master of Science in Clinical Investigation Curriculum Committee |
| 2018-present | Emergency Preparedness Coordinator, McDonnell Genome Institute |
| 2021-present | Member, Research Infrastructure & Applications Governance Committee |
| 2021-present | Member, Biomedical Informatics and Data Science PhD Admissions Committee |
| External Committees | |
| 2006 | Program Committee Member, The RegCreative Conference, Ghent, Belgium |
| 2004-2007 | Member, Let's Talk Science Partnership Program, University of British Columbia |
| 2008 | Sponsorship and Registration Coordinator, Brain Tumor Foundation of Canada |
| 2008-2010 | Founding Member, Open Regulatory Annotation Consortium |
| 2010-2011 | Program Committee Member, NIH ICBP Junior Investigator Meeting |
| 2010-2011 | Program Committee Member, GTC Next Gen Sequencing Conference |
| 2013-2014 | Member, Illumina Sequencing Experts Panel |
| 2013-2016 | Member, Transcription Factor Target Gene Consortium |
| 2013-2016 | Member, Network of Biothings |
| 2016 | Program Co-Chair, Clinical Interpretation Knowledgebase Hackathon and Curation Jamboree, Amsterdam, Netherlands |
| 2014-2017 | Member, Canadian Bioinformatics Workshops Planning Committee |
| 2016-2017 | Member, AACR Annual Meeting Education Committee |
| 2017 | Session Chair, Resources Section, NCI-ITCR Annual Meeting |
| 2018 | ITCR 2018 Annual Meeting Steering Committee |
| 2018 | Cancer Genomics Consortium Annual Meeting Organizing Committee |
| 2017-2018 | Co-Chair, AACR Annual Meeting Program Committee |
| 2017-2018 | Co-Chair, AACR Annual Meeting Education Committee |
| 2018-2019 | Genomics Resource Development Committee, Cancer Genomics Consortium |
| 2019-2020 | Co-Chair, AACR Annual Meeting Program Committee |
| 2019-2020 | Co-Chair, AACR Annual Meeting Education Committee |
| 2012-2020 | Editor, Biostar Consulting LLC |
| 2019-2022 | Communication Committee Chair, Cancer Genomics Consortium |
| 2016-present | Founder/Co-Chair, Variant Interpretation for Cancer Consortium (VICC), GA4GH |
| 2017-present | Board of Directors Member, Cancer Genomics Consortium |
| 2017-present | Steering Committee Member, Global Alliance for Genomic Health |
| 2018-present | Member, ClinGen Cancer Somatic Work Group |
| 2018-present | Member, ClinGen VHL Expert Panel |
| 2018-present | Education Advisory Board Member, bioinformatics.ca |
| 2018-present | Communication Committee Member, Cancer Genomics Consortium |
| 2020-present | Member, AACR Education and Training Committee |
| 2020-present | Member, ClinGen Cancer Variant Interpretation (CVI) Committee |
| 2021-present | Annual Meeting Program Chair, Cancer Genomics Consortium |
| 2021-present | President-Elect, Cancer Genomics Consortium |
| 2022-present | Member, CCDI Molecular Targets Platform Advisory Panel |
| 2022-present | Member, AACR Project SPIRIT Technical Working Group |
| Honors & Awards | |
| 2003-2005 | NSERC PGS-A Award |
| 2003-2005 | MSFHR Junior Trainee Award |
| 2003 | UBC Graduate Entrance Scholarship |
| 2003-2006 | UBC PhD Tuition Fee Award (4 years) |
| 2004 | Albert B. and Mary Steiner Summer Research Award |
| 2004 | CIHR National Poster Competition Award (Silver) |
| 2004 | John Bosdet Memorial Fund Travel Scholarship |
| 2005-2008 | CIHR Canada Graduate Scholarship Doctoral Award |
| 2006 | MSFHR Senior Trainee Award |
| 2007 | Lloyd Skarsgard Research Excellence Prize |
| 2010-2012 | CIHR Fellowship |
| 2015 | University of Winnipeg Annual Alumnus Speaker Award |
| 2015 | National Academy of Sciences Kavli Fellow |
| 2020 | AACR Most-Cited Article Published in 2020 |
| Editorial Boards | |
| Cell Reports | |
| Cancer Genetics | |
| Professional Societies & Organizations | |
| 2010-present | Active Member, American Association for Cancer Research (AACR) |
| 2014-present | Professional Member, International Society for Computational Biology (ISCB) |
| 2016-present | Member, American Society of Human Genetics (ASHG) |
| 2016-present | Member, Cancer Genomics Consortium (CGC) |
| Resources Created | |
| 2006-2022 | ORegAnno - Open Regulatory Annotation (inactive) |
| 2011-2022 | Alexa-Seq - Alternative Expression Analysis of RNA seq (inactive) |
| 2012-present | Bioinformatics Tutorials (biostars.org/u/3737/) |
| 2012-present | Informatics for RNA-seq Analysis online course (rnabio.org) |
| 2013-present | DGIdb – Drug Gene Interaction database (dgidb.org) |
| 2013-present | GMS – Genome Modeling System (github.com/genome/gms/wiki) |
| 2014-present | DoCM – Database of Curated Mutations (docm.info) |
| 2014-present | CIViC – Clinical Interpretation of Variants in Cancer (civicdb.org) |
| 2015-present | GenVisR – Genomic Visualizations in R (github.com/genome) |
| 2016-present | pVACtools – Personalized Cancer Vaccines (pvactools.org) |
| 2017-present | Genomic Visualizations and Interpretations online course (genviz.org) |
| 2018-present | Precision Medicine Bioinformatics online course (pmbio.org) |
