David A. Russler-Germain

David A. Russler-Germain, MD, PhD

Second-year Fellow

Began fellowship in 2019


2005-2009 BS, Stanford University, Stanford, CA
2009-2017 MD/PhD, Washington University School of Medicine, St. Louis, MO
Post-graduate Training
2017-2019 Residency, Internal Medicine, Barnes-Jewish Hospital, St. Louis, MO


  • A Forgotten Friend: CCNU as Palliative Monotherapy in Relapsed Hodgkin Lymphoma
    Russler-Germain DA, Watkins MP, Bartlett NL
    Leuk Lymphoma 2021 Feb;62(2):486-488
  • Incidence of Metastatic Prostate Cancer on the Rise
    Russler-Germain DA, Kahl BS
    Oncology (Williston Park) 2020 Dec 7;34(12):522-534
  • Haploinsufficiency for DNA Methyltransferase 3A Predisposes Hematopoietic Cells to Myeloid Malignancies
    Cole CB, Russler-Germain DA, Ketkar S, Verdoni AM, Smith AM, Bangert CV, Helton NM, Guo M, Klco JM, O'Laughlin S, Fronick C, Fulton R, Chang GS, Petti AA, Miller CA, Ley TJ
    J Clin Invest 2017 Oct 2;127(10):3657-3674
  • CpG Island Hypermethylation Mediated by DNMT3A Is a Consequence of AML Progression
    Spencer DH, Russler-Germain DA, Ketkar S, Helton NM, Lamprecht TL, Fulton RS, Fronick CC, O'Laughlin M, Heath SE, Shinawi M, Westervelt P, Payton JE, Wartman LD, Welch JS, Wilson RK, Walter MJ, Link DC, DiPersio JF, Ley TJ
    Cell 2017 Feb 23;168(5):801-816e13
  • PML-RARA Requires DNA Methyltransferase 3A to Initiate Acute Promyelocytic Leukemia
    Cole CB, Verdoni AM, Ketkar S, Leight ER, Russler-Germain DA, Lamprecht TL, Demeter RT, Magrini V, Ley TJ
    J Clin Invest 2016 Jan;126(1):85-98
  • Registered Report: IDH Mutation Impairs Histone Demethylation and Results in a Block to Cell Differentiation
    Richarson AD, Scott DA, Zagnitko O, Aza-Blanc P, Chang CC, Russler-Germain DA
    Elife 2016 Mar 11;5:e10860
  • The R882H DNMT3A Mutation Associated With AML Dominantly Inhibits Wild-Type DNMT3A by Blocking Its Ability to Form Active Tetramers
    Russler-Germain DA, Spencer DH, Young MA, Lamprecht TL, Miller CA, Fulton R, Meyer MR, Erdmann-Gilmore P, Townsend RR, Wilson RK, Ley TJ
    Cancer Cell 2014 Apr 14;25(4):442-54
  • Microtubules Provide Directional Information for Core PCP Function
    Matis M, Russler-Germain DA, Hu Q, Tomlin CJ, Axelrod JD
    Elife 2014 Aug 14;3:e02893
  • Electron Tomography of Degenerating Neurons in Mice With Abnormal Regulation of Iron Metabolism
    Zhang P, Land W, Lee S, Juliani J, Lefman J, Smith SR, Germain D, Kessel M, Leapman R, Rouault TA, Subramaniam S
    J Struct Biol 2005 May;150(2):144-53