Address: Research Interest: Myeloproliferative neoplasms Research: Myeloproliferative neoplasms (MPNs) are clonal hematologic malignancies typified by genetic alterations that activate JAK-STAT signaling. Chronic MPNs exhibit a propensity for transformation to secondary acute myeloid leukemia (sAML), which carries a dismal prognosis. The overall objective of our work is to better understand the pathogenetic mechanisms responsible for the initiation and … Continue reading Stephen T. Oh, MD, PhD
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