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| Speaker | Date | Title |
|---|---|---|
| Abdul-Nabi, Anmaar | Oct 10, 2008 | Molecular and Biological Effects of AML-associated Fusion Proteins on Primary Human CD34+ Cells |
| Abendschein, Dana | Apr 17, 2015 | Can We Inhibit Thrombosis Without Increasing Bleeding? |
| Agovino, Darby | Apr 20, 2023 | Establishing the Molecular Mechanism of Disease Induced by Mutant ENY2 |
| Agre, Peter | Oct 6, 2022 | Stanley J. Korsmeyer Memorial Lecture: Aquaporin Water Channels: From Atomic Structure to Malaria |
| Ailhaud, Gerard | Mar 23, 2001 | Early Events and Redundancy in Adipogenesis |
| Alford, Shannon | Sep 14, 2007 | Sphingosine 1-phosphate-mediated Endothelial Cell Migration in Human Platelet Poor Plasma |
| Amend, Sarah | Mar 2, 2012 | Identification of the Genetic Basis of MGUS and Multiple Myeloma Susceptibility in KaLwRij Mice |
| Jan 25, 2013 | Of Mice and Men: Genetic Contributions of Susceptibility to MGUS, the Requisite Precursor of Multiple Myeloma | |
| Anbukumar, Dhanam | Feb 3, 2012 | Calcium Binding Studies of von Willebrand Factor Propeptide |
| Nov 16, 2012 | Characterizing VWF Propeptide Ca2+ Binding Sites | |
| Dec 20, 2013 | Cation Dependence of vWF Multimerization | |
| Oct 17, 2014 | A Calcium Conundrum: The Role of Calcium in VWF Multimerization | |
| Dec 10, 2015 | The ATP7A Copper Transporter Is Required for VWF Multimerization | |
| Sep 22, 2016 | Copper Transport in Von Willebrand Factor Biosynthesis | |
| Nov 2, 2017 | The Involvement of Copper Transport in Von Willebrand Factor Biosynthesis | |
| Mar 21, 2019 | The Function of Copper Ions in vWF Multimer Assembly | |
| Anderson, Richard | Apr 21, 2006 | Phosphoinositide Signaling: From Biochemistry to Human Disease |
| Anderson, Trish | Jan 21, 2005 | Work-in-Progress |
| Mar 30, 2007 | ADAMTS13 Structure and Function | |
| Feb 29, 2008 | ADAMTS13 Spacer Domain and Substrate Recognition | |
| Dec 12, 2008 | Substrate Recognition by the ADAMTS13 Spacer Domain | |
| Dec 11, 2009 | More on ADAMTS13 Spacer Domain and VWF Substrate Recognition | |
| Andrews, Nancy | Oct 22, 1993 | An Erythroid Transcription Factor Regulating Globin Gene Expression and Iron Metabolism |
| Oct 23, 1998 | Iron Deficiency and Iron Overload: Insights From Anemic Animals | |
| Armanios, Mary | Jan 31, 2019 | The Telomere Syndromes: Implications for Patient Care |
| Feb 10, 2020 | The Telomere Syndromes: A Paradigm for Molecular Medicine | |
| Arora, Vivek | Dec 17, 2015 | Defining Novel Oncogenic Drug Targets in Bladder Cancer |
| Ataga, Kenneth | Feb 28, 2020 | Meeting Unmet Needs in Sickle Cell Disease |
| Atkinson, John | May 18, 2001 | Immune Adherence Revisited |
| Oct 14, 2005 | HUS: Not Enough Regulation of Innate Immunity | |
| Apr 6, 2012 | Atypical Hemolytic Uremic Syndrome |
| Speaker | Date | Title |
|---|---|---|
| Baenziger, Jacques | May 7, 1999 | The Sulfated Oligosaccharides on LH Reveal the Roles Played by Glycosylation During the Reproductive Cycle |
| Oct 5, 2007 | Carbohydrates Determine Hormone Potency in Vivo | |
| Apr 18, 2014 | Molecular Multi-Tasking: New Insights Into Hepatic Glycan Receptor Function | |
| Baeten, Jeremy | Mar 4, 2021 | TP53 in Clonal Hematopoiesis |
| Mar 3, 2022 | Synergistic Lethality of Decitabine and ATR Inhibition in TP53-Mutant AML | |
| Mar 30, 2023 | Synergistic Lethality of Decitabine and ATR Inhibition in TP53-Mutant AML | |
| Baldo, Guilherme | May 13, 2011 | Pathogenesis of the Aortic Valve Disease in MPS VII |
| Bankaitis, Vytas | Apr 26, 1996 | Phosphatidylinositol Transfer Proteins: a New Class of Intracellular Regulatory Molecules |
| Dec 5, 2007 | A High Resolution Look at a Superfamily of Nanoreactors That Control Phosphoinositide Signaling in Eukaryotic Cells | |
| Baranski, Tom | Feb 25, 2000 | Genetic Analysis of G Protein Signalling |
| Nov 7, 2003 | Understanding the Receptor Switch: How Do Hormones Activate G Proteins? | |
| Barnes, Terra (with Stuart Kornfeld) | Jan 14, 2011 | The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering |
| Bassler, Bonnie L. | Sep 22, 2017 | 9th Rosalind Kornfeld Lecture: Bacterial Quorum Sensing and Its Control |
| Batista, Luis | Mar 21, 2013 | Human IPS Cells as a Model to Study Telomere Dysfunction-Induced Disease |
| May 29, 2015 | Generation of an Isogenic Model to Study the Consequences of Telomerase Mutations in Human Stem Cells | |
| Sep 8, 2022 | Misconduct | |
| Bednarski, Jeffrey | Sep 29, 2016 | Physiologic and Genotoxic DNA Damage Activate Distinct Cellular Responses in Developing B Lymphocytes |
| Beerman, Isabel | Mar 8, 2016 | Hematopoietic Stem Cell Aging |
| Berrien-Elliott, Melissa | Apr 18, 2019 | miR-142 Is Required for NK Cell Homeostasis and Function |
| Bertina, Rogier | Apr 11, 1997 | Genetic Analysis of Inherited Thrombophilia |
| Bessler, Monica | Nov 8, 1996 | Molecular Basis of Paroxysmal Nocturnal Hemoglobinuria |
| Oct 17, 1997 | A Mouse Model for Paroxysmal Nocturnal Hemoglobinuria: Use of the Cre/LoxP System to Circumvent Embryonic Lethality | |
| Mar 26, 1999 | Clonal Evolution in Paroxysmal Nocturnal Hemoglobinuria | |
| Nov 3, 2000 | PNH: the Human Disease and Animal Models | |
| Nov 1, 2002 | Bone Marrow Failure and Telomerase | |
| Jan 14, 2005 | Paroxysmal Nocturnal Hemoglobinuria – From Bench to Bedside | |
| Apr 6, 2007 | Housekeeping Ain’t No Joke! the Importance of Ribosome Biogenesis in Human Blood Disorders | |
| Apr 3, 2009 | Towards a New Understanding of Bone Marrow Failure | |
| Bhattacharya, Deepta | Feb 7, 2014 | Convergent Differentiation During Hematopoiesis |
| Bigg, Paul | Dec 17, 2010 | The Pathogenesis of Mitral Valve Disease in Mucopolysaccharidosis VII Dogs |
| Blumer, Ken | May 7, 2004 | RGS Proteins: New Regulators of Blood Pressure Homeostasis and G Protein-Mediated Vasoconstrictor Signaling |
| Bock, Paul | Sep 22, 2006 | Blood Coagulation Out of Control: Molecular Sexuality Mechanism of Prothrombin Activation by Staphylocoagulase |
| Bock, Susan | Apr 22, 1994 | Antithrombin III and Serpin Structure/Function Studies |
| Boonen, Marielle | Oct 2, 2009 | Mucolipidosis Type II Mice Accumulate Autophagolysosomes in Fibroblasts and Serous/mucous Type Secretory Cells |
| Mar 20, 2015 | Cathepsin D and Neuronal Differentiation: Lessons From the Identification of a New Binding Partner | |
| Bose, Ron | Mar 11, 2011 | Kinase Activation and Signaling: How Does the Her2 Tyrosine Kinase Give Rise to Breast Cancer? |
| Boucher, Paul | Mar 11, 2021 | Adenoviral Vector Mediated Gene Editing of the B Cell Receptor as an HIV Vaccine |
| Mar 9, 2023 | Adenovirus Vectors for B Cell Gene Therapy | |
| Brachmann, Rainer | Oct 9, 1998 | Yeast as a Genetic Tool to Study the Tumor Suppressor Protein P53 |
| Sep 28, 2001 | Stories of and Around P53 | |
| Brakhane, Molly | May 5, 2022 | Role of Calcium Signaling in Hematopoiesis in MPNs |
| May 4, 2023 | Calcium Dysregulation in MPN Platelets | |
| Brass, Skip | May 6, 2011 | Dynamic Regulation of Platelet Accumulation Following Vascular Injury |
| Bray, Paul | Oct 10, 2014 | Platelet PAR4 Functional Genomics: Racial Disparities in Anti-Platelet Therapy |
| Mar 31, 2016 | Plateletomics: Exploring Platelet Biology Via Multi-omic Data Integration | |
| Bredemeyer, Andrea | Oct 15, 2020 | Generation of Yolk-Sac-Like and Definitive Macrophages From Human PSCs |
| Brenner, Kirsten | Feb 13, 2015 | Regulation of the Telomerase RNA Component TERC in Human Development and Disease |
| Mar 24, 2016 | Telomere-Independent Functions of the Telomerase RNA Component in Human Stem Cells | |
| Oct 20, 2016 | Telomere-independent Functions of the Telomerase RNA Component in Human Stem Cells | |
| Oct 12, 2017 | A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells | |
| Sep 27, 2018 | A Telomere-Independent Role for the Telomerase RNA Component in Human Embryonic Stem Cells | |
| Brost, Taylor | May 19, 2016 | Interrogation of Genetically Distinct Clones Using MPN Patient-Specific IPSCs |
| Brown, Ric | Dec 9, 1994 | Signal Transduction by Leukocyte Integrins |
| Broze, George | Oct 4, 1996 | Effects of Tissue Factor and Tissue Factor Pathway Inhibitor Gene Deletion |
| Dec 18, 1998 | What About Protein Z? | |
| Oct 20, 2000 | Protein Z and Thrombosis | |
| Dec 13, 2002 | Regulation of Coagulation by Protein Z | |
| Apr 22, 2005 | TFPI α and β | |
| Mar 9, 2007 | Protein Z-Dependent Protease Inhibitor | |
| Sep 25, 2009 | Regulation of Coagulation | |
| Dec 10, 2010 | Tissue Factor Pathway Inhibitor | |
| Feb 15, 2013 | Translational Studies of Tissue Factor Inhibitors | |
| Bruchas, Michael | Jan 26, 2017 | Dissecting Neuromodulatory Circuits in Affective Behavior |
| Brugge, Joan | Mar 18, 2020 | Oxidative Stress Defenses in Cancer |
| Jan 13, 2023 | Mechanisms of Cancer Therapy Resistance | |
| Brunelli, Angelo | Jan 21, 2021 | Pevonedistat Targets Malignant Cells in Myeloproliferative Neoplasms in Vitro and in Vivo Via NFkB Pathway Inhibition |
| Bu, Guojun | Apr 9, 2004 | The LDL Receptor Family: What These Receptors Don’t Do |
| Byun, Minji | Nov 5, 2015 | Searching for the Genetic Etiology of Infectious Diseases |
| Speaker | Date | Title |
|---|---|---|
| Camargo, Fernando | Nov 17, 2016 | Clonal Analysis of Native Hematopoiesis |
| Feb 9, 2023 | Ancestry and Function in the Hematopoietic System | |
| Challen, Grant | Dec 13, 2013 | The Epigenetics of Hematopoietic Stem Cell Self-Renewal and Transformation |
| Chan, Andy | Mar 4, 1994 | Protein Tyrosine Kinases in T Cell Activation: Bench to Bedside |
| Chang, Sandy | May 7, 2010 | How Telomeres Repress the DNA Damage Response |
| Chang, Shao-Chun | Sep 10, 2004 | The Pathway to Inositol Hexakisphosphate Synthesis |
| Chavez, Monique | Oct 29, 2020 | Investigating Lenalidomide Treatment-Based Secondary B-Cell Acute Lymphoblastic Leukemia |
| Oct 28, 2021 | A Mouse Model of Subclonal Gene Mutations in Myelodysplastic Syndrome | |
| Nov 10, 2022 | The Contribution of Subclonal Gene Mutations in Myelodysplastic Syndrome Progression | |
| Cheng, Emily | Sep 24, 2004 | Apoptotic Checkpoints at the Mitochondrion |
| Dec 14, 2007 | Regulation of Cell Death by BCL-2 Family and Beyond | |
| Cherian, Mathew | Mar 1, 2013 | Role of PI3K-Akt-mTOR in HTLV-Tax Induced Transformation |
| Apr 25, 2014 | Role of the PI3K-Akt mTOR Pathway in Human T Cell Leukemia Induced Transformation | |
| Mar 13, 2015 | Role of the PI3K-Akt-mTOR Pathway in HTLV Induced Leukemogenesis | |
| Cheung, Vivian G. | Oct 27, 2017 | 45th Carl Moore Lecture: It’s in the RNA: Implications for Human Disease |
| Chheda, Milan | Feb 9, 2017 | Developing a Synthetic Lethal Genetic Screen to Identify Vulnerabilities in IDH1 Mutant Gliomas |
| Chiquetto, Luana | Feb 17, 2022 | The Role of Stathmin-1 in the Regulation of HSCs |
| May 4, 2023 | The Role of Stathmin-1 in Regulation of HSCs | |
| Choi, Jaebok | Jan 20, 2012 | Interferon Gamma Receptor Signaling and T Cell Trafficking in Graft vs. Host Disease |
| Choi, Kyunghee | Apr 20, 2012 | Regulation of Hematopoietic and Vascular Development |
| Cho, Jaehyung (Gus) | Feb 14, 2020 | Mechanisms Regulating Intravascular Cell-Cell Interactions in Thrombosis and Inflammation |
| Christopher, Matt | Apr 10, 2015 | Cold Shock Domain Proteins in Normal and Malignant Hematopoiesis |
| Feb 11, 2016 | WT1 in Normal and Malignant Hematopoiesis | |
| Clevers, Hans | Mar 2, 2016 | 43rd Carl Moore Lecture: Lgr5 Stem Cell-Grown Organoids and Their Applications |
| Cocco, Lucio | Apr 30, 2010 | Nuclear Phospholipase C Beta1 Signalling, MDS and AML: From Bench to Clinics |
| Cole, Christopher | Mar 22, 2013 | Role of DNMT3A in Acute Promyelocytic Leukemia |
| Mar 28, 2014 | The Role of Dnmt3a in Acute Promyelocytic Leukemia | |
| Collier, Timothy | May 3, 2013 | Probing the Structure and Dimerization of EGFR Family Tyrosine Kinases |
| Collins, Taylor | Feb 16, 2017 | Utilizing iPSCs as a Model System to Interrogate Genetically Distinct Clones in Myeloproliferative Neoplasms |
| Oct 5, 2017 | Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs | |
| Dec 13, 2018 | Interrogation of ASXL1 Mutations in Combination With the JAK2 V617F Mutation in MPNs | |
| Sep 19, 2019 | Interrogating the Role of ASXL1 and JAK2 Mutations in MPNs Utilizing Human Pluripotent Stem Cells | |
| Cooper, John | Jan 19, 1996 | Control of Actin Assembly by Capping Protein |
| Cordes, Ethan | Nov 10, 2022 | TGS1 Depletion Increases Telomerase RNA Stability in Dyskeratosis Congenita |
| Cottrell, Kyle | Apr 18, 2019 | Upregulation of 5’TOP mRNAs Following Loss of the Tumor Suppressor ARF |
| Crabtree, Gerald | Nov 9, 2012 | 40th Carl Moore Lecture: Chromatin Regulation: New Methods and Concepts |
| Creamer, Philip | Feb 1, 2018 | Investigating Gene Expression During Human Definitive Hematopoietic Specification |
| Feb 14, 2019 | Defining the Role of CDX4 During Human Definitive Hematopoietic Specification | |
| Crispino, John | Apr 6, 2023 | Mechanisms of Leukemogenesis in Down Syndrome |
| Crowley, Stephanie | May 13, 2021 | BCLAF1 Regulation of Hematopoietic Stem Cell Repopulating Capacity |
| Apr 7, 2022 | Bclaf1 Promotes Hematopoietic Stem Cell Repopulating Capacity | |
| Cummings, Rick | Feb 2, 1996 | The Glycobiology of Schistosomiasis: From Molecular Mimicry to Autoimmunity |
| Speaker | Date | Title |
|---|---|---|
| Dahms, Nancy | Feb 27, 1998 | Insight Into Lysosomal Enzyme Recognition by the Mannose 6-Phosphate Receptors |
| Dalla-Favera, Riccardo | Oct 10, 2017 | Stanley J. Korsmeyer Memorial Lecture: Molecular Genetics of B Cell Lymphoma |
| Dang, Luke | Mar 19, 2010 | Two Histidine Residues Required for the pH Dependent Multimerization of Von Willebrand Factor |
| Das Thakur, Meghna | Mar 16, 2007 | The Role of LIM Proteins in Cell-Cell Adhesion and Epithelial Polarity |
| May 16, 2008 | Role of the Ajuba LIM Protein in Size Control in Drosophila Epithelia | |
| Davidson, Nick | May 30, 2003 | RNA Editing: Molecular Mechanisms and Biological Consequences |
| Day, Ryan | Feb 4, 2021 | Distinct Profiles of CBF Leukemias |
| Dean, Doug | Feb 16, 1996 | Mechanism of Action of the Retinoblastoma Tumor Suppressor |
| Oct 26, 2001 | The Role for Rb in Tumor Suppression | |
| Dege, Carissa | May 5, 2016 | Characterization of Human Pluripotent Stem Cell Derived Natural Killer Cells |
| Oct 27, 2016 | Generation and Characterization of Human Pluripotent Stem Cell-derived Natural Killer Cells | |
| Oct 12, 2017 | Natural Born Killers? Determining Function and Ontological Origins of Two Distinct Natural Killer Cell Populations Derived From Human Pluripotent Stem Cells | |
| Sep 27, 2018 | Ontogeny Is a Critical Determinant of Human Pluripotent Stem Cell Derived Natural Killer Cell Function | |
| Oct 3, 2019 | Potently Cytotoxic Natural Killer Cell Potential Initially Emerges From Erythro-Myeloid Progenitors During Mammalian Development | |
| Degen, Jay | May 10, 1996 | Hard Knocks to the Hemostatic Balance: Fibrinogen and Plasminogen Deficiency in Mice |
| DeNardo, David | Sep 6, 2013 | Reprogramming Macrophages to Improve Responses to Chemo- and Immunotherapy |
| DePinho, Ronald | Dec 8, 2000 | 28th Carl Moore Lecture: Telomerase, Tumor Suppressors and Tumorigenesis |
| Deuel, Tom | Mar 29, 1996 | Mechanisms of Transcriptional Regulation by the Wilms Tumor Suppressor Gene |
| Jun 1, 2011 | Shaping the Tumor Phenotype and Microenvironment: New Pathways, New Therapeutic Targets | |
| DeWeerd, Rachel | Mar 18, 2021 | The Experimentally-Defined APOBEC3A Signature Is Prevalent in Human Cancers |
| Di Cera, Enrico | Feb 13, 1998 | Thrombin Allostery |
| Oct 8, 2004 | Rational Design of a Thrombin Mutant With Potent and Safe Anticoagulant/Antithrombotic Activity in Vivo | |
| Diacovo, Tom | Dec 10, 1999 | Platelets and the Molecular and Cellular Interactions Governing Their Adhesion: From Arterial Injury to Venular Inflammation |
| Dick, John | Nov 19, 1993 | Modeling Normal and Leukemic Hematopoiesis in SCID Mice |
| Dietz, Hal | Nov 19, 2010 | 38th Carl Moore Lecture: TGFβ in the Pathogenesis and Prevention of Aneurysm: Embracing Paradox |
| Dinauer, Mary | Mar 9, 2012 | Getting a License to Kill: Regulation of the Leukocyte NADPH Oxidase |
| DiPaola, Jorge | Jan 7, 2019 | Studying Megakaryocytes, From Inherited Disorders to Old Age Platelets |
| DiPersio, John | Dec 19, 1997 | Cytokine Signaling Pathways |
| Dolatshahi, Leili | Feb 22, 2013 | Adjuvant Low Dose Rituximab for Patients with TTP |
| Doray, Balraj | Jan 7, 2005 | Work-in-Progress |
| Mar 3, 2006 | Work-in-Progress | |
| Feb 2, 2007 | The α/σ2 Hemicomplex of Clathrin Adaptor AP-2 Harbors the Dileucine Recognition Site | |
| Oct 26, 2007 | Identification of Acidic-dileucine Signals That Bind to GGAs and AP-1/AP-2 | |
| Feb 13, 2009 | Understanding the GGA Null Phenotype | |
| Dec 11, 2009 | Characterization of Mouse GGA2 Antibodies | |
| Mar 4, 2011 | GGA Autoinhibition Re-revisited: Do Internal Dileucines Bind GGA VHS Domains | |
| Feb 17, 2012 | GGA Null Mice: The Final Chapter? Or Not? | |
| Jan 11, 2013 | Gga2 Knockout Mice Revisited | |
| Dec 20, 2013 | Influence of Genetic Background on Lethality of GGA2 Knockout Mice | |
| Nov 14, 2014 | Assembly of UDP-GlcNAc-1-Phosphotransferase, a Multi-Subunit Protein | |
| Sep 10, 2015 | Understanding How GlcNAc-1-Phosphotransferase Recognizes Lysosomal Enzymes: Part I | |
| Nov 4, 2021 | Insight Into Regulation of GlcNAc-1-Phosphotransferase Function as Revealed Through Cryo-EM Analysis | |
| Doudna, Jennifer | Nov 13, 2015 | 8th Rosalind Kornfeld Lecture: The CRISPR-Cas9 Genome Engineering Revolution |
| Druker, Brian | Mar 3, 2000 | CML and STI 571: Validating the Promise of Molecularly Targeted Therapy |
| Dubielecka, Patrycja | Oct 17, 2019 | Signaling at the Crossroads: From Inflammaging to Cancer |
| Duckett, Colin | Apr 24, 2001 | Role of IAP Proteins in the Control of Cell Survival |
| Du, Hong-Yan | Oct 28, 2005 | Work-in-Progress |
| Feb 9, 2007 | TERT Haploinsufficiency and Telomere Length in Individuals with 5p- Syndrome | |
| Jan 18, 2008 | The Significance of Telomere Length Measurement in the Diagnosis of Dyskeratosis Congenita | |
| Dunbar, Andrew | Mar 16, 2023 | Molecular Pathogenesis and Therapy of Myeloproliferative Neoplasms |
| Duncavage, Eric | Feb 28, 2014 | Detection of Subclonal Population in MDS |
| Oct 31, 2014 | Sequencing Based Detection of Low Frequency Variants in MDS | |
| Dustin, Mike | Jun 4, 1999 | Visualizing Molecular Events in the Immune Response: Building an Immunological Synapse |
| Du, Xiaoping | Sep 2, 2021 | Novel Mechanisms of Integrin Outside-In Signaling and the Concept of Treating Thrombosis and Inflammation Without Causing Bleeding |
| Speaker | Date | Title |
|---|---|---|
| Elefanty, Andrew | Aug 30, 2018 | Dissection of Human Haematopoiesis From Pluripotent Stem Cells |
| Elf, Shannon | Nov 17, 2022 | Type 1 and Type 2 Calreticulin Mutations Activate Discrete Unfolded Protein Response Pathways to Drive Myeloproliferative Neoplasms |
| Mar 28, 2023 | The Pathobiology of Type 1 Versus Type 2 Calreticulin-Mutated Myeloproliferative Neoplasms | |
| Ellenberger, Tom | Feb 8, 2008 | Chemical Biology of DNA Repair |
| Ellisen, Leif | Mar 24, 2000 | Acute Leukemia, Telomeres and DNA Damage Responses |
| Ellis, Matthew | Oct 4, 2013 | The Genomics and Proteomics of Breast Cancer |
| Engle, Elizabeth | May 3, 2013 | Genetic Complexity and Clonal Evolution in Myeloproliferative Neoplasms |
| May 23, 2014 | Genetic Complexity and Disease Evolution in Myeloproliferative Neoplasms | |
| Feb 27, 2015 | Intersection of Dysregulated Cytokines and Signaling in Myeloproliferative Neoplasms | |
| Epple, Holly | May 5, 2006 | Work-in-Progress |
| Jan 19, 2007 | From the Skeleton to the Cytoskeleton: Mechanisms of Osteoclast Function |
| Speaker | Date | Title |
|---|---|---|
| Fager, Ammon | Jan 11, 2016 | Human Platelets Express Endothelial Protein C Receptor Which Contributes to the Binding and Activity of rFVIIa |
| Fehniger, Todd | Nov 1, 2013 | Molecular Regulation of NK Cell Development and Function |
| Feng, Yunfeng | May 13, 2005 | Work-in-Progress |
| Oct 13, 2006 | RNAi Oriented Loss of Function Research on α-Actinin | |
| Feb 29, 2008 | Regulation of Cell Migration by α-actinin | |
| Feys, Hendrik | May 16, 2008 | Understanding ADAMTS13 When Under (Shear) Stress |
| Field, Joshua | Apr 4, 2014 | The Potential Role of Invariant NKT Cells in Sickle Cell Disease |
| Fields, Melanie | May 8, 2015 | MR Measurements of Cerebral Blood Flow and Oxygen Extraction Fraction in Pediatric Sickle Cell Disease |
| Apr 21, 2016 | Functional Connectivity in Sickle Cell Disease | |
| Mar 30, 2017 | Cerebral Oxygen Metabolism and Vasoreactivity in Sickle Cell Disease | |
| Fisher, Daniel | Jan 20, 2012 | Mass Cytometry Study of Human Myeloproliferative Neoplasia |
| Oct 26, 2012 | Genomic Study of Myeloproliferative Neoplasia | |
| Feb 14, 2014 | Signaling in Myeloproliferative Neoplasms Studied by Single Cell Mass Cytometry | |
| Sep 26, 2014 | Mass Cytometry Study Identifies NFκB Signaling as a Potential Disease Driver in Myeloproliferative Neoplasms | |
| Sep 10, 2015 | NFkB Hyperactivation in Myeloproliferative Neoplasms | |
| Apr 13, 2017 | Cytokines and Intracellular Signaling Abnormalities in Myeloproliterative Neoplasms | |
| Jan 25, 2018 | Utilizing Mass Cytometry and Mouse Models to Understand Myeloproliferative Neoplasms | |
| Jan 24, 2019 | Interacting Roles of Hyperactive Signaling and Cytokine Overproduction in Myeloproliferative Neoplasms | |
| Jan 30, 2020 | NFκB Hyperactivation in Myeloproliferative Neoplasms: Insights From Human Patients and Mouse Models | |
| Sep 17, 2020 | NF kappa B Hyperactivation in Myeloproliferative Neoplasms | |
| Sep 23, 2021 | JAK2 and NF Kappa B Hyperactivation in Mouse Hematopoiesis and Myeloproliferative Neoplasms | |
| Flaumenhaft, Robert | Mar 9, 2020 | Test Tube to Trial: Protein Disulfide Isomerase as an Antithrombotic Target |
| Fleischman, Angela | Sep 28, 2017 | Inflammation as a Driver of Clonal Expansion in Myeloproliferative Neoplasm |
| Fok, Wilson | Nov 14, 2014 | Telomere Dysfunction in Stem Cell Proliferation and Differentiation |
| Oct 15, 2015 | Telomere Dysfunction in Stem Cell Proliferation and Differentiation | |
| Sep 22, 2016 | p53 Stabilization Following Progressive Telomere Shortening Differentially Regulates Human Hematopoietic Specification | |
| Oct 5, 2017 | Understanding How Telomere Dysfunction and RNA Processing Defects Lead to Human Disease | |
| Oct 25, 2018 | Inhibition of Polyadenylation Activity by Silencing of PAPD5 Restores Telomerase and Rescues Hematopoietic Failure in Dyskeratosis Congenita | |
| Fowles, Jared | Apr 27, 2017 | Genomic Dissection of Age-Related Differences in Polycythemia Vera |
| Feb 1, 2018 | Genomic Dissection of Age-Related Differences in Polycythemia Vera | |
| Feb 21, 2019 | Investigating the Genomic and Inflammatory Profiles of Young and Old Polycythemia Patients | |
| Nov 5, 2020 | Dysregulated Inflammation in Myeloproliferative Neoplasms and Disease Progression | |
| Frazier, Bill | Oct 13, 1995 | Thrombospondin as a Regulator of Endothelial Phenotype |
| Mar 22, 2002 | Integrin Associated Protein (CD47): a Receptor With Multiple Roles in Vascular Disease | |
| French, Anthony | Apr 3, 2015 | Regulation of NK Cell Proliferation |
| Friedman, Jeffrey | Oct 24, 1997 | 25th Carl Moore Lecture: Leptin, Leptin Receptors and the Control of Body Weight |
| Fuh, Katherine | Mar 31, 2016 | Functional Genomics of Ovarian Cancer Metastasis |
| Fujiki, Yukio | Mar 5, 2010 | Peroxisome Biogenesis and Its Dysfunctions in Humans |
| Speaker | Date | Title |
|---|---|---|
| Gadue, Paul J. | Apr 5, 2018 | Megakaryocyte Development From Stem Cell Sources |
| Gailani, Dave | Apr 7, 1995 | The Role of Factor XI in a Revised Model of Blood Coagulation |
| Mar 26, 2010 | Factor XI and the Intrinsic Pathway in Normal and Pathologic Coagulation | |
| Ganem, Donald | Nov 21, 2008 | 36th Carl Moore Lecture: Small Noncoding RNAs and the Biology of Kaposi’s Sarcoma-Associated Herpesvirus |
| Ganz, Tomas | Jan 23, 2015 | Systemic Iron Homeostasis and Its Disorders |
| Gao, Weiqiang | Oct 21, 2005 | Work-in-Progress |
| Sep 15, 2006 | A C-terminal Exosite of von Willebrand Factor Domain A2 Interacts with ADAMTS13 Spacer Domain to Accelerate Substrate Cleavage | |
| Oct 26, 2007 | Contacts Between Several ADAMTS13 Structural Domains and Von Willebrand Factor Domain A2 Contribute to Substrate Cleavage | |
| Apr 10, 2009 | Fluorescent VWF Substrates for ADAMTS13 | |
| May 21, 2010 | Functional Differences of the Non-Catalytic Domains in Human ADAMTS13 and ADAMTS5 in Substrate Cleavage | |
| Gao, Xin | Feb 14, 2023 | Regulation of Hematopoietic Stem Cell Mobilization by the Bone Marrow Niche |
| Ge, Jingping | May 4, 2007 | Study of the Function of Dyskerin in a Liver Specific Knock-out Mouse Model |
| Apr 11, 2008 | Is Dyskerin Essential for Cell Survival and Proliferation? | |
| Jan 30, 2009 | Microarray Analysis of snoRNA Expression in Dyskerin Knockout Mice | |
| Feb 5, 2010 | The Consequences of Dyskerin Ablation in Mouse Liver | |
| Germain, David | May 23, 2014 | DNMT3A Mutations in AML |
| Geuze, Hans | Dec 16, 1993 | New Observations on the Class II Compartment in B Lymphoblasts |
| Gilligan, Diana | Mar 7, 2000 | Knockout of Beta-Adducin Causes Spherocytosis in Mice |
| Gilliland, Gary | Oct 14, 1994 | Early Mutations in Leukemia |
| Ginsburg, David | Feb 21, 2003 | Disorders of Hemostasis Due to Genes Outside of the Coagulation System |
| Jan 7, 2021 | FV/FVIII and Cargo Receptors in the ER: From Bedside to Bench | |
| Girard, Tom | Jan 7, 2011 | The Ups and Downs of Protein Z and the Z-dependent Protease Inhibitor |
| Feb 3, 2012 | Tissue Factor Pathway Inhibitor – βefore and αfter | |
| Nov 16, 2012 | Protein Z, Protein Z-Dependent Protease Inhibitor (SerpinA10) and the Acute Phase Response | |
| Oct 25, 2013 | Tissue Factor Pathway Inhibitor Structures, Functions and Physiology | |
| Sep 5, 2014 | Impact of Coagulation Regulators in Mouse Models of Various Diseases | |
| Dec 10, 2015 | Evaluating Blockade of the Protein Z-Dependent Protease Inhibitor Pathway as a Potential Treatment for Hemophilia | |
| Jan 12, 2017 | The Roles of Tissue Factor Pathway Inhibitor in Health and Disease | |
| Feb 15, 2018 | A Balance Between Pro- and Anti-Coagulant Factors to Abate Bleeding and Avoid Thrombosis | |
| May 2, 2019 | The TFPIαβ (γKO) Mouse Is a Better Model for Studying Human TF-Related Diseases | |
| Giri, Tusar | Mar 10, 2006 | Work-in-Progress |
| Gitlin, Jonathan | May 9, 1997 | Aceruloplasminemia |
| Oct 6, 2000 | The Copper Chaperones | |
| May 2, 2008 | Copper Homeostasis in Early Development | |
| Glimcher, Laurie | Oct 31, 2019 | Stanley J. Korsmeyer Memorial Lecture: ER Stress: Reprogramming the Tumor Microenvironment |
| Goate, Alison | Jan 13, 2006 | A Novel Risk Factor for Alzheimer’s Disease on Chromosome 10 |
| Goldberg, Dan | Apr 24, 1998 | The Pathway of Hemoglobin Degradation in the Malaria Parasite P. falciparum |
| Jan 10, 2003 | Falciparum Malaria: a Hematological Infectious Disease | |
| Apr 4, 2008 | Targeting Intraerythrocytic Malaria Parasites for Chemical Destruction | |
| Dec 14, 2012 | Trial by Fire and Famine: How the Malaria Parasite Survives in Its Host Erythrocyte | |
| Goldsmith, Mark | Jun 9, 1994 | Structure/Function Relationships Within the IL-2 Receptor Complex |
| Gopalan, Priya | Oct 10, 2008 | Regulation of Hematopoietic Stem Cells by the Bone Marrow Niche |
| Govero, Jennifer | Apr 18, 2008 | Characterization of the GGA Null Mice |
| Nov 14, 2008 | Characterization of the GGA Null Mice | |
| Mar 19, 2010 | All GGAs Are Not Created Equal | |
| Feb 4, 2011 | Strain Dependent Lethality of GGA2 Null Mice: Embryonic vs Neonatal | |
| Grainger, Stephanie | Apr 20, 2021 | From Fish to Dish and Back Again: Deciphering Wnt/Fzd Cues in Hematopoietic Stem Cell Development |
| Graubert, Tim | Mar 14, 2003 | Modeling T(8;21) Associated Acute Myelogenous Leukemia in Mice |
| May 23, 2008 | Genetic Basis of Susceptibility to Therapy-Related Leukemia | |
| Greenberg, Zev | Feb 28, 2019 | Regulation of Early B Cell Development by the Tetraspanin CD53 |
| Jan 30, 2020 | Loss of CD53 Impairs B Cell Migration | |
| Apr 21, 2022 | The Tetraspanin CD53 Protects Hematopoietic Stem Cells Following Cellular Stress Through Induction of DREAM Complex-Mediated Quiescence | |
| Green, Eric | Nov 11, 2005 | 33rd Carl Moore Lecture: Comparative Genomics: Using Evolution to Decode the Human Genome |
| Grierson, Patrick | May 9, 2019 | Overcoming the MK2/ Hsp27 Axis to Potentiate the Effect of Chemotherapy in Pancreatic Ductal Adenocarcinoma (PDAC) |
| Jan 9, 2020 | The MK2/Hsp27 Axis Determines Sensitivity to Chemotherapy in Pancreatic Ductal Adenocarcinoma | |
| Gu, Baiwei | Oct 27, 2006 | Molecular Mechanism of Mouse Dyskerin Mutation in Telomere Maintenance and Ribosomal RNA Processing |
| Oct 12, 2007 | Dyskerin, Telomerase and DNA Damage | |
| Sep 19, 2008 | Is Dyskerin Crucial for Telomere Maintenance, DNA Damage Response and Ageing? | |
| Sep 18, 2009 | DNA Damage Accumulation, Accelerated Hematopoietic Stem Cell Aging, and Partial Reversal by Antioxidant Treatment in a Mouse Model of Dyskeratosis Congenita | |
| Gu, Minxiang | Jun 12, 1998 | Characterization of a Novel Protein Tyrosine Phosphatase – PTPMEG |
| Gupta, Garima | Mar 1, 2013 | Non-catalytic Interaction Between VWF and ADAMTS-13 |
| Speaker | Date | Title |
|---|---|---|
| Hahn, William | Apr 21, 2000 | Telomerase Immortality in Cancer |
| Hajjar, Kathy | Apr 8, 1994 | Annexin II: a New Thromboregulatory Protein? |
| Halldorsdottir, Anna Margret | Sep 30, 2005 | Work-in-Progress |
| Hambleton, Julie | Apr 5, 1996 | Activation of MAP Kinase Signaling Pathways in Monocyte/Macrophage Cells |
| Hancock, John | Mar 3, 1995 | Ras Proteins: Membrane Targeting and Biochemical Function |
| Sep 17, 1999 | Caveolae, Cholesterol and Trafficking: New Insights Into Biological Differences Between the Ras Proteins | |
| Harris, David | May 23, 1997 | Prion Diseases: a Cell Biological Perspective |
| Feb 22, 2002 | Molecular Mechanisms Underlying Familial Prion Diseases | |
| He, Fan | Feb 11, 2021 | The Characteristics of Platelets in Essential Thrombocythemia |
| Feb 10, 2022 | The Metabolic Dysregulation of Platelets in MPN Disease | |
| Mar 2, 2023 | Single-Cell Analysis Reveals Galectin-1 as a Novel Monocyte Marker and Therapeutic Target in MPN | |
| Heinecke, Jay | Jan 11, 2002 | Regulation of Matrix Metalloproteinase Activation and Plaque Rupture by Myeloperoxidase |
| He, Jun | Feb 18, 2005 | Work-in-Progress |
| May 19, 2006 | Work-in-Progress | |
| Heldermon, Coy | Sep 5, 2008 | The Effect of Bone Marrow Transplant and Intracranial Gene Therapy in Mucopolysaccharidosis IIIB Mice |
| He, Li | Apr 29, 2005 | Work-in-Progress |
| Herzog, Brett | Oct 24, 2019 | Reactive Fibrosis in Lung Cancer: Impact on Immunity and Progression |
| Apr 15, 2021 | Restoring Immune-Mediated Tumor Control in the Fibrotic NSCLC Microenvironment | |
| Heslop, Helen | Apr 21, 1995 | Use of Virus-Specific Cytotoxic T Lymphocytes to Control Epstein-Barr Virus-Related Lymphoproliferation |
| High, Katherine | Apr 12, 1996 | Gene Therapy for Hemophilia |
| Jan 25, 2012 | Biologic Therapeutics/Hematology Joint Seminar: in Vivo Gene Transfer for Genetic Disease: Progress and Challenges | |
| Hiken, Jeff | Mar 16, 2007 | Proteomic Analysis of PNH RBCs |
| Feb 15, 2008 | Label-free Quantitative Proteomic Analysis of Normal and PNH RBC Membranes | |
| Oct 24, 2008 | Quantitative Differences Between Expression Profiles of RBC Proteomes | |
| Hirbe, Angela | May 9, 2014 | Defining the Molecular Events Underlying Malignant Transformation in NF1-related MPNSTs Through Whole Genome Sequencing |
| Mar 13, 2015 | Whole Exome Sequencing Reveals the Temporal Sequence of Genetic Changes During Malignant Transformation and Metastasis in a Single Patient With NF1-Associated Plexiform Neurofibroma | |
| Hobbs, Helen | Nov 12, 2019 | Mechanisms of Lipid Accumulation: Implications for Fatty Liver Disease |
| Hockemeyer, Dirk | Feb 13, 2020 | Elucidating the Mechanisms of Cancer Cell Immortality |
| Hoffmeister, Karin | Feb 17, 2020 | Glycans in Translational and Clinical Research |
| Hofmann, Sandra | May 9, 1996 | Palmitoyl-Protein Thioesterase and the Pathogenesis of INCL |
| Sep 19, 2014 | Phil Majerus Symposium: Molecular Basis of Infantile Batten Disease | |
| Hogg, Phil | Apr 3, 2002 | Control of Von Willebrand Factor Multimer Size by Thrombospondin-1 |
| Horwich, Arthur | Nov 16, 2007 | 35th Carl Moore Lecture: Protein Folding and Misfolding in the Cell |
| Howe, Ruth | May 14, 2010 | The Role of Cathepsin S and MMP-12 in MPS VII Aortic Disease |
| Hsieh, Jim | Nov 5, 2004 | Taspase1 Cleaves Mixed-Lineage Leukemia Proto-Oncogene |
| Jan 25, 2008 | Taspase1 Links MLL Proteolysis to Cell Cycle Progression and Beyond | |
| Huang, Jing | Mar 2, 2007 | αvβ3 Integrin is Involved in the Stabilization of Shear-induced Ultra-long VWF Strings on Endothelial Surface |
| Nov 9, 2007 | The B Subunits of Shiga Toxins Induce Von Willebrand Factor Secretion and Cytoskeletal Remodeling in Human Endothelial Cells | |
| Oct 24, 2008 | The B-subunits of Shiga-like Toxins 1 and 2 Promote VWF Secretion Via a Cholesterol Sensitive, Clathrin-independent Mechanism in Human Endothelial Cells | |
| Oct 2, 2009 | The B Subunits of Type 1 and Type 2 Shiga-like Toxins Induce Regulated VWF Secretion in a Phospholipase D Dependent Manner | |
| Sep 17, 2010 | The B Subunits of Shiga-like Toxins Induce Regulated VWF Secretion in a Phospholipase D1 Dependent Manner | |
| Sep 16, 2011 | Cells as a Model System to Study Weibel-Palade Body Targeting and Regulated Secretion of Ultra-large von Willebrand Factor | |
| Sep 28, 2012 | Distinct Functions of pH-Sensing Histidine Residues in the Multimer Assembly and Storage of von Willebrand Factor in Weibel-Palade Bodies | |
| Sep 20, 2013 | The Distinct Role of Two pH Sensing Histidines in the Multimer Assembly and Tubular Storage of von Willebrand Factor | |
| Huang, Ren-Huai | Feb 24, 2006 | Work-in-Progress |
| Feb 2, 2007 | How VWF Propeptide and D’D3 Domain Assemble the Storage Rings in Weibel-Palade Bodies | |
| Sep 14, 2007 | Assembly and Structure of Von Willebrand Factor Tubules in Weibel-Palade Bodies | |
| Sep 19, 2008 | Structural Basis of VWF for Aptamer Binding and Tubular Storage | |
| Sep 18, 2009 | A Structural Explanation for the Antithrombotic Activity of ARC1172, a DNA Aptamer that Binds Von Willebrand Factor Domain A1 | |
| Feb 18, 2011 | Calcium and pH-Dependent Interactions Within VWF Tubule | |
| Dec 2, 2011 | Von Willbrand Factor Assembly by D-domains Before Furin Cleavage | |
| Oct 12, 2012 | How Von Willebrand Factor is Condensed into Weibel-Palade Bodies | |
| Nov 8, 2013 | VWF Tubular Assembly in Vitro by D Domains | |
| Sep 5, 2014 | The Role of D Domains in VWF Tubule Assembling | |
| Jan 28, 2016 | pH-Dependent Association Within N-terminal D Domains of Von Willebrand Factor | |
| Hugge, Chris | Apr 15, 2005 | Work-in-Progress |
| Hultgren, Scott | Mar 12, 2004 | Intracellular Bacterial Communities in Bacterial Infections |
| Speaker | Date | Title |
|---|---|---|
| Idol, Rachel | May 12, 2006 | Work-in-Progress |
| Jan 12, 2007 | Investigations of Ribosomal Biogenesis in Diamond Blackfan Anemia | |
| Sep 28, 2007 | Human Ribosomal Biogenesis | |
| Feb 27, 2009 | A Mouse Model of Diamond Blackfan Anemia | |
| Apr 2, 2010 | Mouse Models of Diamond Blackfan Anemia | |
| May 27, 2011 | Phenotypic Analysis of Phosphotransferase Deficient Mice | |
| May 11, 2012 | Uncovering New Phenotypes in Uncovering Enzyme-Deficient Mice | |
| Apr 19, 2013 | CNS Defects in Mice Lacking Mannose-6-Phosphate | |
| Iglesia, Michael | Apr 22, 2021 | Breast Cancer Subtype Heterogeneity at the Single-Cell Level |
| Iglesia, Michel | Jan 6, 2022 | Precursor Populations and Transitional States in Breast Cancer |
| Apr 27, 2023 | Metastasis in Colorectal Cancer: Tumor Microenvironment and Treatment Effects | |
| Ihle, Jim | Oct 21, 1994 | JAKs and STATs in Cytokine Signaling |
| Ikawa, Yogi | Nov 21, 1995 | A Possible New Erythropoietin Receptor Signaling Pathway in Friend Erythroleukemia |
| Ikeda, Kazuhiko | Apr 18, 2008 | Overexpression of HMGA2 in Normal and PNH Hematopoietic Cells |
| Dec 12, 2008 | Overexpression of HMGA2 in Normal and PNH Hematopoiesis | |
| Jan 8, 2010 | Myeloproliferative Neoplasm-like Hematopoiesis in Mice with Truncated Hmga2 cDNA | |
| Iliopoulos, Othon | Feb 18, 2000 | Functional Analysis of the Von Hippel-Lindau Tumor Suppressor Protein |
| Imai, Shin-Ichiro | Feb 10, 2012 | Towards Productive Aging: the Importance of SIRT1 and NAMPT-Mediated NAD Biosynthesis in the NAD World |
| Speaker | Date | Title |
|---|---|---|
| Jacoby, Meagan | Mar 13, 2009 | DNA Repair Genes in Treatment-related AML and MDS |
| Jan 21, 2011 | DNA Repair Dysfunction in Primary Therapy-related AML/MDS Myeloblasts | |
| Mar 30, 2012 | Dysfunctional Double Strand Break Repair is Present in a Subset of Therapy-related MDS/AML Myeloblasts | |
| Feb 22, 2013 | Dysfunctional Double Strand Break Repair in Therapy-related AML | |
| Apr 11, 2014 | Investigating DNA Double-Strand Break Repair in MDS and AML | |
| Jagannathan, Radhika | Mar 4, 2011 | Negative Regulation of the Salvador-Warts-Hippo Pathway by the Ajuba LIM Family of Proteins |
| Dec 16, 2011 | Negative Regulation of the Hippo Pathway by the Ajuba LIM Family of Proteins | |
| Jasinski, Marek | Mar 18, 2005 | Work-in-Progress |
| Jay, Patrick | Sep 24, 2015 | Solving Congenital Heart Disease |
| Jefferson, A. B. | Sep 29, 1995 | Cell Signalling and the Inositol Polyphosphate 5-Phosphatase Isozymes |
| Jennings, Ben | Dec 12, 2019 | Identifying Molecular Mechanisms Regulating the Localization of Golgi Glycosyltransferases |
| Oct 1, 2020 | Molecular Mechanisms Regulating the Localization of SARS-CoV2 Spike Protein and Golgi Glycosyltransferases | |
| Sep 29, 2022 | A Weak ER Retrieval Motif in SARS CoV-2 Spike Protein Mediates Both New Virus Infectivity and Cell-Cell Spreading | |
| Jeong, Hochang | Apr 25, 2019 | Determining Therapeutic Targets to Restore Hematopoietic Output in Dyskeratosis Congenita |
| Jan 9, 2020 | USB1 Mutation Causes Defective Hematopoiesis | |
| Jan 28, 2021 | Human ESC Modeling of Poikiloderma With Neutropenia Unveils Defective Hematopoietic Development Caused by Mutation in USB1 | |
| Sep 16, 2021 | USB1 Is a miRNA Deacetylase That Regulates Hematopoietic Development | |
| Sep 29, 2022 | USB1 Is a miRNA Deadenylase That Regulates Hematopoietic Development | |
| Jha, Vishwanath | May 20, 2021 | Role of Platelet ERO1α in Platelet Activation and Arterial Thrombosis |
| May 19, 2022 | Role of Platelet ERO1α in Platelet Activation and Arterial Thrombosis | |
| Jin, Bo | Apr 27, 2007 | Studies on the von Willebrand Factor Cysteine Knot Domain |
| Mar 28, 2008 | Structural Basis of VWF Cleavage by ADAMTS13 | |
| Jin, Ramon | Dec 12, 2019 | Patient-Derived Organoids to Study Barrett’s Esophagus and Esophageal Carcinogenesis |
| Apr 8, 2021 | The Role of SOX2 in Barrett’s Esophagus and Esophageal Adenocarcinoma | |
| Johanns, Tanner | May 5, 2016 | An Immunogenomic Approach to Identify Glioblastoma-Specific CD8 T Cells |
| Feb 2, 2017 | Effect of Prior Radiation on Gliomagenesis and Tumor Immunity | |
| Dec 14, 2017 | Neoantigens as Therapeutic Targets in Glioblastoma | |
| Johansson, Kim | May 12, 2022 | Idasanutlin and Navitoclax Induce Synergistic Cell Death in T-ALL Patient-Derived Xenografts |
| Mar 23, 2023 | Is Ribosomal Stress a Therapeutic Vulnerability in T-ALL? | |
| Feb 28, 2023 | Biology and Therapeutic Targeting of Myeloproliferative Neoplasms |
| Speaker | Date | Title |
|---|---|---|
| Kadyrov, Farid | Jan 14, 2021 | The Effects of Hypoxia on Monocyte/Macrophage Specification and Function During Ischemic Heart Injury |
| Kang, Yoon | Mar 30, 2021 | Who Does the Work? Lineage-Biased MPPs Tailor Blood Production |
| Jan 13, 2022 | Decoding Lineage Specification Mechanisms in Hematopoietic Stem and Multipotent Progenitor Populations | |
| Karue, Julie | May 14, 2010 | Function of the N-terminal Domain of Heparin Cofactor II |
| Katerndahl, Casey | Apr 26, 2018 | The Mechanisms Underlying PML-RARA-Induced Transformation and Self-Renewal |
| May 9, 2019 | The Mechanisms Underlying PML-RARA-Induced Self-Renewal and Transformation | |
| Kaufman, Charles | Mar 23, 2017 | Key Events During Cancer Initiation: From Melanocyte to Melanoma |
| Kaufman, Randal | May 20, 1994 | Regulation of Protein Transport Through the Endoplasmic Reticulum Mediated by BiP |
| Kaushansky, Ken | Nov 4, 1994 | The Molecular and Cellular Biology of Thrombopoietin, the MPL-Ligand |
| Keating, Mark | Nov 19, 1999 | 27th Carl Moore Lecture: Molecular and Cellular Mechanisms of Cardiac Arrhythmias |
| Kelly, Dan | Apr 23, 1999 | The Role of PPAR Alpha as a ‘Lipostat’ Transcription Factor |
| Mar 26, 2004 | PPAR Gamma Coactivator-1 (PGC-1): an Inducible Regulator of Cardiac Mitochondrial Biogenesis and Function | |
| Kenyon, Cynthia | Jan 6, 2012 | 4th Rosalind Kornfeld Lecture: Genes and Cells That Affect the Rate of C. Elegans’ Aging |
| Kharas, Michael | Apr 14, 2016 | RNA Binding Proteins and the Control of the Leukemic Stem Cell Program |
| Khoriaty, Rami | Jul 20, 2016 | Congenital Dyserythropoietic Anemia Type II and Transport of Proteins from the ER to Golgi |
| Kim, Alfred | Jan 14, 2016 | Glomerular Podocyte Cytokine Signaling Drives Proteinuria: Implications in Nephrotic Syndromes |
| Kim, Brian | Jan 21, 2016 | Immune Regulation of Atopic and Chronic Itch |
| Kim, Jae-Sung | Apr 13, 2023 | The Role of RIPK1 in Platelet Activation and Arterial Thrombosis |
| Kim, Jeeseung | May 25, 2023 | MPP3 Subset Is Novel Source of Plasma Cell |
| Kim, Jongseong | Jan 15, 2013 | Single-Molecule Mechanobiology of Von Willebrand Factor (VWF) to Arbitrate Between Bleeding, Hemostasis, and Thrombosis |
| Kisseleva, Marina | Feb 4, 2005 | Work-in-Progress |
| Oct 27, 2006 | Macrophages Plagued by LIM Protein Deficiency | |
| Jan 8, 2010 | Regulation of Nuclear PI(5)P in Stress Signaling | |
| Oct 15, 2010 | O, Brother, Where Art Thou? MTMR8 and MTMR9 Journey Inside the Cell | |
| Klausner, Richard | Nov 15, 1996 | 24th Carl Moore Lecture |
| Koenig, Andrew | Feb 18, 2021 | Cellular Atlas of the Failing Human Heart |
| Kohn, Donald | Nov 17, 1995 | Gene Therapy With Hematopoietic Stem Cells |
| Koh, Won Kyun | Sep 24, 2020 | Non-Canonical Role of DNMT3A in HSC Function |
| Sep 30, 2021 | Non Canonical Role of DNMT3A in HSC Function | |
| Kolhouse, Fred | Mar 18, 1994 | The Mechanism of Cellular Uptake of Folate and Methotrexate in Human Cells |
| Kong, Tim | Jan 20, 2022 | Comprehensive Profiling of Clinical JAK Inhibitors in Myeloproliferative Neoplasms |
| Kopan, Raphael | Mar 10, 2000 | Signaling Through Notch – a Proteolytic Cascade Regulating Cell Fate |
| Feb 13, 2004 | Multiple Roles for Notch in Mouse Development and Tissue Renewal | |
| Kornfeld, Kerry | Nov 20, 1998 | A Modular System of Docking Sites Mediates MAP Kinase Recognition of Substrate Proteins |
| Jan 29, 2010 | The Role of Zinc in Animal Development and Physiology | |
| Kornfeld, Rosalind | Feb 7, 1997 | Enzymes of Glycoprotein Oligosaccharide Processing |
| Jan 29, 1999 | Cloning and Expression of N-Acetylglucosamine-1-Phosphodiester α-N-Acetylglucosaminidase, a Key Enzyme in Formation of the Mannose-6-Phosphate Targeting Signal | |
| Sep 22, 2000 | The Mannose 6-Phosphate “Uncovering Enzyme” Resides in the Trans-Golgi Network | |
| Kornfeld, Stuart (with Terra Barnes) | Jan 14, 2011 | The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering |
| Kornfeld, Stuart | Oct 18, 1996 | Protein Trafficking To and From Lysosomes |
| Apr 9, 1999 | Clathrin-Coated Vesicle Formation on Liposomes and Golgi Membranes | |
| Nov 17, 2000 | The Assembly of Clathrin-Coated Vesicles on Golgi Membranes | |
| Oct 11, 2002 | GGAs – Key Players in Packaging Man-6-P Into Transport Vesicles | |
| Mar 11, 2005 | The GGA Family of Coat Proteins – Key Players in Protein Sorting at the Trans-Golgi Network | |
| Nov 3, 2006 | Toward a Chaperone-based Therapy for Gaucher Disease | |
| Jan 20, 2009 | New Insights Into the Man-6-P Lysosomal Enzyme Targeting System From Mouse Models | |
| Feb 1, 2013 | New Insights Into the Man-6-P Lysosomal Targeting Pathway Through Analysis of Mutations in I-Cell Disease and Pseudo-Hurler Polydystrophy | |
| Feb 6, 2015 | Role of the γ Subunit of UDP-GlcNAc:Lysosomal Enzyme GlcNAc-1-Phosphotransferase in Lysosomal Enzyme Phosphorylation | |
| Kramer, Michael | Nov 18, 2021 | Analysis of the Proteome of De Novo Acute Myeloid Leukemia |
| Jan 26, 2023 | Proteomics of Pre-Leukemic and Leukemic Hematopoietic Cells With AML-Associated DNMT3A and/or NPM1 Mutations | |
| Kumari, Tripti | Oct 21, 2021 | Identification of an Inhibitor of PDI-GPIbα Signaling as a Novel Anti-Thromboinflammatory Agent |
| Oct 27, 2022 | Role of SGLT1/2 on Intravascular Cell-Cell Aggregation and Vaso-Occlusion Mediated Conditions in Mouse Model of Sickle Cell Disease | |
| Kunter, Ghada | Mar 18, 2011 | Molecular Pathogenesis of Leukemia in Severe Congenital Neutropenia |
| Speaker | Date | Title |
|---|---|---|
| Langer, Ellen | Apr 1, 2005 | Work-in-Progress |
| Apr 27, 2007 | Ajuba LIM Proteins are Snail Corepressors that Contribute to Xenopus Neural Crest Development | |
| Laranjeira, Angelo | Nov 11, 2021 | Pevonedistat Targets Malignant Cells in Myeloproliferative Neoplasms in Vitro and in Vivo Via NFκB Pathway Inhibition |
| Jan 19, 2023 | Dysregulated Signaling Pathways in Myeloproliferative Neoplasms | |
| Lavine, Kory | Feb 18, 2016 | Making Sense of Cardiac Macrophage Ontogeny and Function |
| Lawn, Richard | Oct 28, 1993 | Lipoprotein(a) |
| Lederkremer, Gerardo | Apr 7, 1999 | Location and Regulation of ER/Proteasomal Protein Quality Control |
| Lee, Angel | Nov 12, 1993 | CSF-1 Receptor: Mechanisms of Intracellular Signalling |
| Lee, Intaek | Oct 13, 2006 | Crosstalk Between Two Cargo Binding Sites of Adaptor Protein Complex AP-1 |
| Sep 28, 2007 | Binding of Cargo Sorting Signals to AP-1 Enhances its Association with ARF1-GTP | |
| Sep 5, 2008 | The Role of the Gamma-subunit of UDP-GlcNAc:lysosomal Enzyme N-acetylglucosamine-1-phosphotransferase | |
| Lee, Jingu | May 25, 2023 | Role of Neutrophil CRACR2A in Neutrophil Recruitment During Inflammation |
| Lee, Wang-Sik | Feb 4, 2005 | Work-in-Progress |
| Mar 30, 2007 | Studies of a Mouse Model with I-cell Disease and Pseudo-Hurler Polydystrophy | |
| Apr 25, 2008 | IFG, a Potential Therapeutic Agent for Gaucher Disease, Reduces Cholesterol Accumulation in Neimann-Pick C1 Fibroblasts | |
| May 8, 2009 | The Role of the γ-Subunit of GlcNAc-Phosphotransferase | |
| Oct 1, 2010 | Update of the Uncovering Enzyme Research with Stutterers’ mutations | |
| Sep 16, 2011 | Update on Studies of Mutations Found in the Gene Encoding Uncovering Enzyme in Individuals with Persistent Stuttering | |
| Apr 5, 2013 | Structure and Function of the DUF2233 Domain in Bacteria and in Human UCE | |
| Apr 11, 2014 | Analysis of Missense Mutations in the α,β-Subunit of GlcNAc-Phosphotransferase Associated with Stuttering | |
| Feb 13, 2015 | The Mannose 6-Phosphate Lysosomal Targeting Pathway and Persistent Stuttering | |
| Jan 28, 2016 | Role of the Subunits of GlcNAc-Phosphotransferase in Lysosomal Enzyme Recognition | |
| Feb 27, 2020 | Analysis of Lysosomal Storage Disease-Causing Missense Mutations Within the Transmembrane Domain of GlcNAc-1-Phosphotransferase | |
| Lefkowitz, Bob | Nov 16, 2001 | 29th Carl Moore Lecture: G Protein-Coupled Receptors and Their Regulation |
| Lentz, Steven | Oct 24, 2001 | Hyperhomocysteinemia |
| Feb 3, 2020 | Vascular Stress Management: Oxidative Mechanisms in Thrombosis and Stroke | |
| Levine, Beth | Oct 11, 2013 | 6th Rosalind Kornfeld Lecture: Novel Links Between Autophagy Proteins, Cell Biology, and Metabolism |
| Levy, Joanne | Apr 7, 2000 | Iron Metabolism: Insights From Mutant Mice |
| Ley, Tim | Jan 14, 2000 | How Do Cytotoxic Lymphocytes Kill Their Target? |
| Dec 13, 2001 | Modeling Acute Promyelocytic Leukemia in the Mouse | |
| Oct 5, 2011 | Interdisciplinary Seminar Series: the AML Genome | |
| Li, Anguo | Mar 14, 2008 | Differential Gene Expression of Injured Arteries in HCII Knockout Mice |
| Jan 22, 2010 | Activation of Heparin Cofactor II by Fibroblast Proteoglycans | |
| Lifton, Richard | Nov 8, 2002 | 30th Carl Moore Lecture: New Insights Into Cardiovascular, Renal, and Bone Disease From Human Genetic Studies |
| Lim, Kian-Huat | May 1, 2015 | Toll-like Receptor Signaling in Human Cancer |
| Linder, Maurine | Mar 1, 1996 | G-Protein Palmitoylation: Reversible and Regulated Acylation |
| Linette, Gerry | Jan 25, 2002 | Melanoma Cell Death |
| Link, Dan | May 5, 1995 | G-CSF Receptor Signals |
| Nov 14, 1997 | Role of G-CSF in Hematopoiesis: Lessons From the G-CSF Receptor Knockout Mice | |
| Mar 7, 2003 | Regulation of Hematopoiesis by G-CSF | |
| Nov 30, 2007 | Regulation of the Hematopoietic Stem Cell Niche by G-CSF | |
| Oct 8, 2010 | Regulation of Stem Cell and Neutrophil Trafficking From the Bone Marrow | |
| Oct 19, 2012 | Characterizing the Stem Cell Niche | |
| Jan 27, 2020 | Pathogenesis of Congenital Neutropenia and Mechanisms of Leukemic Transformation | |
| Lippincott-Schwartz, Jennifer | Nov 6, 2020 | Imaging Interacting Organelles to Understand Metabolic Homeostasis |
| Littman, Dan | Nov 15, 2013 | 41st Carl Moore Lecture: Shaping of the Immune Response by the Commensal Microbiota |
| Liu, Chang | Apr 27, 2017 | Single-Molecule HLA Typing by Oxford Nonopore Technology |
| Mar 29, 2018 | Rapid High-Resolution HLA Typing by Nanopore Sequencing | |
| Liu, Fang | Jan 4, 2008 | The Characteristic of Signaling Pathways Involved in Stx B-induced von Willebrand Factor Secretion |
| Mar 13, 2009 | Cell Signaling in Stx B Subunit-induced VWF Secretion | |
| May 28, 2010 | The Mechanism of VWF Basolateral Secretion in HUVECs | |
| Liu, Lin | Apr 7, 2016 | Uncovering Novel Regulatory Roles of the “Spacer 1” Region of the GlcNAc-1-Phosphotransferase |
| Apr 13, 2017 | Producing Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy | |
| Apr 12, 2018 | Golgi Retention of Glycosyltransferases Requires Binding of Its N-Terminal Cytoplasmic Tail to Coatomer | |
| Li, Weikai | May 4, 2012 | Structure and Function of Vitamin K Epoxide Reductase: Connecting Oxidative Protein Folding With Blood Coagulation |
| Li, Yedda | Mar 24, 2016 | Combination Therapy Increases Lifespan and Improves Clinicobehavioral Performance in the Murine Model of Globoid Cell Leukodystrophy |
| Mar 2, 2017 | Combination Therapy Improves Lifespan and Clinicobehavioral Performance in Murine Globoid Cell Leukodystrophy | |
| Longmore, Greg | Nov 1, 1996 | Erythropoietin Receptor Signalling and Red Cell Development |
| May 8, 1998 | Cytokine Regulation of Lineage Commitment During Hematopoiesis | |
| Feb 26, 1999 | Role of LIM Proteins in Cell Growth | |
| Apr 20, 2001 | Red Blood Cell Development and Leukemogenesis | |
| Jan 24, 2003 | The Role of Lim Proteins in Cell Adhesion and Motility | |
| Dec 17, 2004 | Role of LIM Proteins in Cell Adhesion and Migration | |
| Jan 26, 2007 | LIM Proteins and Epithelial Development and Cancer | |
| Sep 11, 2009 | Epithelial Morphogenesis in Development and Cancer | |
| Jan 28, 2011 | Epithelial Morphogenesis in Development and Disease | |
| Look, Tom | May 19, 1995 | Chimeric Transcriptional Control Genes in Human Acute Leukemia |
| Lopez, Jose | Apr 13, 2021 | The Significance of Endothelium-Bound von Willebrand Factor |
| Luderer, Hilary | Feb 3, 2006 | Work-in-Progress |
| Nov 10, 2006 | LIMD1: a New Key to Understanding Skeletal Dynamics | |
| Luff, Stephanie | Mar 15, 2018 | Twice Spliced: Exploring HOXA9 Variants in Embryonic Hematopoiesis |
| Feb 28, 2019 | Recapitulating Intraembryonic Hematopoiesis in the Dish | |
| Oct 24, 2019 | Top Notch Blood: The Involvement of NOTCH Signaling in Extra-Embryonic Hematopoiesis | |
| Lunn, Cara | Nov 12, 2010 | Discovery of Mutations in Myelodysplastic Syndrome Genomes |
| Nov 11, 2011 | U2AF1 Mutations in Myelodysplastic Syndromes | |
| Sep 14, 2012 | U2AF1 Splicing Factor Mutations in Myelodysplastic Syndromes | |
| Lu, Rong | Jan 3, 2013 | Systems Analysis of Mouse Hematopoietic Stem Cells in Vivo at the Single Cell Level |
| Lyons, Susan | Feb 9, 2001 | Hematopoietic Studies in the Zebra Fish Model |
| Speaker | Date | Title |
|---|---|---|
| MacArthur, Craig | Jan 30, 1998 | FGF-8 in Development and Tumorigenesis |
| Mackman, Nigel | Apr 1, 2022 | Mechanisms of Cancer-Associated Thrombosis recording (mp4) |
| Madison, Blair | Feb 23, 2017 | PLAGL2, a Zinc Finger Transcription Factor That Drives Stem Cell Identity and Colorectal Cancer Tumorigenesis |
| Majerus, Elaine | Oct 22, 2004 | Regulation of VWF Cleaving Protease (ADAMTS13) Activity |
| Feb 17, 2006 | Work-in-Progress | |
| May 18, 2007 | Studies on ADAMTS13 | |
| Apr 17, 2009 | Studies on ADAMTS13 and Protein O-Fucosyltransferase 2 | |
| Apr 8, 2011 | Studies With an Enhancer of VWF Cleavage – a Novel Potential Anti-Thrombotic? | |
| Majerus, Phil | Sep 20, 1996 | Role of Inositol Phosphates in Intracellular Signalling |
| May 21, 1999 | Phosphatidyl Inositols in Cell Signaling | |
| Apr 6, 2001 | Intracellular Signaling by Inositol Phosphates | |
| Sep 13, 2002 | Inositol Signaling | |
| Dec 10, 2004 | Inositol Phosphate Signaling | |
| Mar 23, 2007 | Phosphatidylinositol Signaling and Human Disease | |
| Jan 9, 2009 | Inositols Do It All | |
| Nov 5, 2010 | Inositol Signaling in Human Disease | |
| Mallaney, Cates | Apr 25, 2014 | Interactions Between Dnmt3a and Repressive Chromatin Regulate Hematopoietic Stem Cell Function and Transformation |
| Jan 30, 2015 | Interactions Between Dnmt3a and Repressive Chromatin Regulate Hematopoietic Stem Cell Function and Transformation | |
| Mann, Ken | Dec 16, 1994 | Modeling the Tissue Factor Pathway to Thrombosis: the Coagulation Explosion |
| Marjanovic, Jasna | Apr 13, 2007 | Phosphatidylinositol-5-phosphate is a Novel Phospholipase C (PLC) Substrate |
| Feb 15, 2008 | Characterization of Myotubularin Related Protein 8 | |
| Nov 11, 2011 | Work-in-Progress | |
| Mason, Phil | Nov 10, 2000 | The Molecular Genetics of Dyskeratosis Congenita |
| Mar 6, 2003 | Bone Marrow Failure Caused by Inherited Telomerase Deficiency | |
| Mar 25, 2005 | Bone Marrow Failure Caused by Inherited Defects in Telomerase | |
| Apr 20, 2007 | Telomeres, Ribosomes and Bone Marrow Failure | |
| Nov 7, 2008 | Telomeres, Ribosomes and Bone Marrow Failure | |
| Mast, Alan | Nov 19, 2015 | Tissue Factor Pathway Inhibitor Biochemistry and Relation to Bleeding and Clotting Disorders |
| Apr 27, 2021 | The TFPI Anticoagulant Activity Modulates Cerebrovascular Development | |
| Mathias, Brendan | Mar 17, 2022 | MYSM1 in DNA Damage Signaling During B Cell Development |
| Ma, Xiucua | Mar 2, 2007 | Mechanism of Up-regulation of MMP-12 and Cathepsin S in the Aorta of Mucopolysaccharidosis I Mice |
| May 9, 2008 | A Self-inactivating Retroviral Vector with Improved Safety for Gene Therapy in Mucopolysaccharidosis I Mice | |
| McCaffrey, Anton | Apr 7, 2006 | Keep It Down: There’s More Than One Way to Silence a Gene |
| McCormick, Frank | May 12, 2016 | Stanley J. Korsmeyer Memorial Lecture: New Ways of Targeting Ras |
| McDonald, Sharon | May 8, 2009 | Investigating the Interaction of Dyskerin and Pot1b |
| McLemore, Morgan | Mar 9, 2001 | The Effect of Granulocyte Colony-Stimulating Factor Receptor (G-CSFR) Mutations on Granulopoiesis |
| McLeod, Howard | Mar 8, 2002 | Cancer Pharmacogenomics |
| Mecham, Bob | Oct 27, 1995 | Intracellular Forms of Extracellular Proteins: Novel Pathway for Cell Regulation |
| Sep 12, 2003 | Developmental Adaptation of the Mouse Cardiovascular System to Elastin Haploinsufficiency | |
| Nov 4, 2011 | Regulation of Growth Factor Activity by Extracellular Matrix | |
| Metcalf, Jason | Sep 15, 2006 | The Role of Fibroblast Growth Factor Signaling in Mucopolysaccharidosis Bone Defects |
| May 9, 2008 | Pathogenesis of Short Bones in Mucopolysaccharidosis VII | |
| May 15, 2009 | A New and Safer Gene Therapy Vector for Mucopolysaccharidosis I | |
| Michel, Loren | Mar 7, 2008 | Oncogenic Role and Therapeutic Targeting of the Transmembrane Protein Trop-2 in Epithelial Tumors |
| Mikulka, Christina | Apr 26, 2018 | Cell-Autonomous Expression of the Lysosomal Enzyme GALC in the Twitcher Mouse |
| Mar 28, 2019 | Cell-Autonomous Expression of the Lysosomal Hydrolase GALC: A New Model of Krabbe Disease | |
| Milbrandt, Jeff | Nov 21, 2003 | Ret Signaling in Development and Disease |
| Millman, Jeffrey | Oct 29, 2015 | Generation of Functional Human Pancreatic β Cells from Pluripotent Stem Cells In Vitro |
| Mills, Jason | Oct 8, 2015 | Stem Cells, Reprogramming, and the Origins of Cancer |
| Min, Sang | Mar 9, 2015 | Role of Phosphoinositides in Platelet-Mediated Inflammation and Thrombosis |
| Monlish, Darlene | Oct 25, 2018 | Differential Effects of TLR1/2 and TLR2/6 Signaling on Normal and Premalignant Hematopoietic Stem and Progenitor Cells |
| Morceau-Gaudry, Francois | Nov 22, 2002 | Gene Therapy of a Mouse Model of Protoporphyria With an Erythroid-Specific Lentiviral Vector |
| Morrissey, James | Mar 23, 2012 | Platelet Polyphosphate at the Nexus of Blood Clotting and Inflammation |
| Mosammaparast, Nima | Feb 4, 2016 | Ubiquitin Dependent Regulatory Mechanisms in the Alkylation Damage Response |
| Muglia, Lou | Dec 2, 2005 | Glucocorticoid Receptor Action During Inflammation |
| Muia, Joshua | Feb 17, 2012 | An Optimized Fluorogenic Assay for ADAMTS13 and Inhibitors in Thrombotic Thrombocytopenic Purpura Patients |
| Jan 11, 2013 | pH Dependent Activity of ADAMTS13 and Self-regulatory Mechanisms | |
| Mar 28, 2014 | ADAMTS13 is Conformationally Autoinhibited by its Distal Domains and is Allosterically Activated by Von Willebrand Factor | |
| Jan 30, 2015 | Insights Into ADAMTS13 Diversity Across Multiple Animal Species | |
| Oct 15, 2015 | In Search of the Minimalist ADAMTS13 Using Evolutionary Variations in its Allosteric Properties | |
| Oct 20, 2016 | Evolution and Allosteric Regulation of ADAMTS13 | |
| Nov 30, 2017 | Two Metalloproteases Involved in Cardiovascular Disease | |
| Oct 11, 2018 | Insights Into the Structure and Regulation of a Metalloprotease Involved in Cardiovascular Disease | |
| Mullally, Ann | Feb 9, 2012 | Characterizing and Therapeutically Targeting MPN Stem Cells in Vivo |
| Mullaney, Cates | Jan 7, 2016 | The Role of Kdm6b in Hematopoiesis |
| Munroe, Michael | Sep 10, 2020 | Telomere Dysfunction Inpairs Hepatocyte Development and Function Via Repression of HNF4A |
| Murphy, Ken | Mar 6, 2015 | Dendritic Cell Diversification |
| Muslin, Tony | Oct 31, 1997 | The Role of 14-3-3 Protein in Ras-Mediated Signal Transduction |
| Oct 24, 2003 | Signaling Protein Function in Cardiovascular Disease | |
| Mysorekar, Indira | Apr 20, 2017 | Understanding Pathogenesis of Maternal Fetal Transmission of the Emerging Zika Virus |
| Speaker | Date | Title |
|---|---|---|
| Nandakumar, Satish | Feb 23, 2021 | How Can We Learn About Healthy and Diseased Hematopoiesis From Human Genetic Studies? |
| Ndonwi, Matthew | Apr 15, 2005 | Work-in-Progress |
| Jan 20, 2006 | Work-in-Progress | |
| Mar 28, 2008 | Effect of Protein S on Tissue Factor Pathway Inhibitor (TFPI) Activity | |
| Jan 16, 2009 | Malarial Histidine Rich Protein II (HRPII) and Blood Coagulation | |
| Oct 16, 2009 | Effect of Malarial Histidine-rich Protein II (HRPII) on Blood Coagulation | |
| Oct 15, 2010 | Interaction of TFPI with Factor V | |
| Oct 14, 2011 | Studies on Lipoprotein-free and Lipoprotein-associated Plasma Tissue Factor Pathway Inhibitor | |
| Nesheim, Mike | Apr 19, 1996 | Isolation, Characterization, and Thrombin-thrombomodulin Dependent Activation of TAFI |
| Neufeld, Elizabeth | Oct 31, 2008 | 1st Rosalind Kornfeld Lecture: Four Decades of Research on MPS |
| Niero, Evandro | Mar 2, 2017 | Teleomere Shortening Impairs Hepatocyte Differentiation by DNA Damage Signaling Activation |
| Nolta, Jan | Jan 30, 2004 | Immune Deficient Mouse Models for Studying Human Hematopoietic Stem Cell Biology |
| Norris, Andy | Apr 10, 1998 | The Regulation of PI 3-Kinase Signaling by Inositol Polyphosphate 4-Phosphatases |
| Novack, Deb | Jan 10, 2014 | NIK’ing the Bone: Mechanisms for Control of the Osteoclast |
| Speaker | Date | Title |
|---|---|---|
| O’Leary, David | Apr 28, 2022 | Loss of SMC5/6 Sensitizes Leukemia Cells to APOBEC3A Cytosine Deaminase Activity |
| O’Shea, Erin | Sep 10, 2010 | 3rd Rosalind Kornfeld Lecture: Translating DNA Sequence Into Gene Expression Output |
| Odom, Audrey | Oct 23, 2009 | Essential Isoprenoids in Plasmodium Falciparum Malaria |
| Oh, Steve | May 20, 2011 | The Missing LNK: Mechanisms of Dysregulated Signaling in Myeloproliferative Neoplasms |
| May 18, 2012 | JAK2 and Beyond: Genomics and Signaling in Myeloproliferative Neoplasms | |
| Mar 29, 2013 | Towards an Understanding of Genetic and Phenotypic Complexity in Myeloproliferative Neoplasms | |
| Orkin, Stuart | Nov 11, 1994 | 22nd Carl Moore Lecture: Multi-layered Regulation of Hematopoietic Development and Transcription |
| Orlowski, Rachel | Mar 27, 2009 | Studies with Protein O-fucosyltransferase 2 |
| Ornitz, Dave | Oct 7, 1994 | Regulation of FGF/FGF Receptor Activity |
| Apr 19, 2002 | FGF and FGF Receptor Signaling in Skeletal Development and Genetic Disease | |
| Ory, Dan | Nov 20, 2009 | The Niemann-Pick C Pathway: a Key Regulator of Cholesterol Homeostasis |
| Speaker | Date | Title |
|---|---|---|
| Parks, Bill | Jan 16, 2004 | Extracellular Proteolysis in Epithelial Repair and Defense |
| Payton, Jackie | Oct 18, 2013 | Targeting the Malignant Epigenome in B Cell Lymphoma |
| Permutt, Alan | Feb 28, 1997 | Genetic Analysis of Monogenic and Polygenic Disorders of Glucose Metabolism |
| Pham, Christine | Dec 16, 2005 | Neutrophil Serine Proteases: Specific Regulatory Effectors of Immunity |
| Pike, Linda | May 2, 2003 | EGF Receptors and Lipid Rafts: Bringing Order to Chaos |
| Jan 15, 2010 | Bi-Directional Signaling in the EGF Receptor | |
| Piwnica-Worms, David | May 5, 2000 | Molecular Imaging: Functional Identification of MDR1 Pgp Transport Activity in Tumors and Tissues in Vivo |
| Piwnica-Worms, Helen | May 2, 1997 | Reversible Phosphorylation and Cell Cycle Control |
| Sep 26, 2003 | Cell Cycle- and Checkpoint-Control: the CHK1/CDC25A Regulatory Pathway | |
| Feb 11, 2011 | Translation of Fundamental Cell Cycle Principles to Targeted Cancer Therapies | |
| Ponder, Kathy | Dec 13, 1996 | Gene Therapy for Plasma Protein Deficiencies |
| Mar 12, 1999 | Hepatic Gene Therapy for Plasma Protein Deficiencies and Lysosomal Storage Diseases | |
| Feb 2, 2001 | Degradation of Hepatocyte Nuclear Factor 4 Contributes to Liver Failure | |
| May 9, 2003 | Liver-Directed Gene Therapy Corrects Hemophilia B and Mucopolysaccharidosis VII in Dogs | |
| Jan 28, 2005 | Reducing Immune Responses After Gene Therapy for Genetic Diseases | |
| Nov 17, 2006 | Gene Therapy for Mucopolysaccharidosis | |
| Jan 23, 2009 | The Pathogenesis of Disease in Mucopolysaccharidosis | |
| Apr 22, 2011 | The Pathogenesis of Mucopolysaccharidosis May Involve Complement Activation | |
| Apr 12, 2013 | The Effect of Gene Therapy for Mucopolysaccharidosis After a Decade | |
| May 22, 2015 | Central Nervous System-Directed Gene Therapy for Mucopolysaccharidosis VII | |
| Pratt, Steve | Jan 21, 2005 | Work-in-Progress |
| Prescott, Steve | Sep 19, 2014 | Phil Majerus Symposium: Lipid Messengers: I Met Them in St. Louis |
| Preston, Roger | Oct 18, 2012 | Regulating the Regulator: Modulating Activated Protein C Functions for Therapeutic Gain |
| Prusiner, Stanley | Nov 5, 1993 | 21st Carl Moore Lecture: Transgenetic and Protein Structural Approaches to Unraveling the Enigmas of Prion Diseases |
| Purvis, Angie | Jan 7, 2005 | Work-in-Progress |
| Apr 14, 2006 | Work-in-Progress | |
| May 4, 2007 | Identification of Cysteine Residues Essential for von Willebrand Factor (VWF) Multimerization: an Elephant is Born | |
| Apr 11, 2008 | Von Willebrand Factor: the Free Thiol Saga Continues | |
| Feb 13, 2009 | pH Dependence of VWF Multimerization and Storage |
| Speaker | Date | Title |
|---|---|---|
| Qian, Monica | Jan 22, 2010 | Functions of the α, β and γ Subunits of UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-Phosphotransferase |
| Dec 17, 2010 | UDP-GlcNAc:Lysosomal Enzyme N-Acetylglucosamine-1-Phosphotransferase | |
| Dec 16, 2011 | Functions of the α, β and γ Subunits of UDP-G1cNAc:Lysosomal Enzyme N-acetylglucosamine-1-phosphotransferase | |
| Oct 26, 2012 | Missense Mutations in Mucolipidosis II and Mucolipidosis III | |
| Nov 8, 2013 | Analysis of Mutations in MLII and MLIII α/β Patients – a New Way to Study Lysosomal Enzyme Sorting |
| Speaker | Date | Title |
|---|---|---|
| Ramsingh, Giri | May 15, 2009 | Characterizing MicroRNAs in Acute Myeloid Leukemia |
| Randi, Anna | Apr 26, 2013 | Von Willebrand Factor Regulates Angiogenesis and Endothelial Progenitors’ Function |
| Ratner, Lee | Jan 28, 2000 | Human T-Cell Leukemia Virus Tax, Transactivation, and Transformation |
| Jan 11, 2008 | T-Cell Activation and Lymphoma | |
| Razani, Babak | Apr 6, 2017 | Macrophages Epitomize Firefighter Arsonists in Metabolic Diseases. Can We Promote Better Behavior? |
| May 6, 2021 | Dietary Protein and Amino Acid-Mediated mTOR Signaling in Atherosclerosis | |
| Rice-Boucher, Paul | Mar 10, 2022 | Adenoviral Vector Mediated Gene Editing of the B Cell Receptor as an HIV Vaccine |
| Richardson, Chris | Apr 4, 2018 | The Fanconi Anemia Pathway Plays a Key Role in DNA Repair at CRISPR-Cas9 Cut Sites |
| Ricketts, Lindsay | Jan 12, 2007 | O-fucosylation of ADAMTS13 |
| Riehl, Terry | Nov 12, 2010 | COX-1+/-COX-2-/- Genotype in Mice is Associated with Shortened Time to Carotid Artery Occlusion Through Increased PAI-1 |
| Robledo, Sara | Apr 13, 2007 | The Role of Ribosomal Proteins in the Pathogenesis of Diamond Blackfan Anemia |
| Mar 14, 2008 | The Role of Human Ribosomal Proteins in the Maturation of rRNA and Ribosome Production | |
| Rohrer, Jack | Dec 15, 1995 | Sorting of Proteins in the Endosomal/Lysosomal System |
| Rondina, Matthew | Jan 31, 2020 | Platelet Transcriptomics as Discovery Tools in Human Health and Disease |
| Mar 9, 2022 | MHC-I Antigen Presentation by Platelets Suppresses CD8+ T Cells During Sepsis | |
| Rosenfeld, Michael | Dec 8, 1995 | 23rd Carl Moore Lecture: Transcriptional Mechanisms of Organ Commitment |
| Rowley, Janet | Oct 10, 2003 | 31st Carl Moore Lecture: New Paradigms From Leukemias |
| Ruggeri, Zaverio | Sep 30, 1994 | Mechanisms of Initiation of Platelet Thrombus Formation |
| Russler-Germain, David | Apr 24, 2015 | Molecular Consequences of DNMT3A Mutations in AML |
| Feb 25, 2021 | Novel Mutations Contributing to Follicular Lymphoma | |
| Feb 24, 2022 | Updating Our Clinico-Genomic Understanding of Follicular Lymphoma | |
| Apr 27, 2023 | Clinicogenomics of Follicular Lymphoma |
| Speaker | Date | Title |
|---|---|---|
| Sabatini, David | Nov 21, 2014 | 42nd Carl Moore Lecture: Regulation of Growth by the mTOR Pathway |
| Sadler, Evan | Feb 21, 1997 | Thrombin Structure and Biological Function |
| Jan 22, 1999 | Enteropeptidase, Initiator of a Digestive Protease Cascade | |
| Jan 12, 2001 | Structure and Function of Von Willebrand Factor | |
| Sep 27, 2002 | Von Willebrand Factor, ADAMTS13, and Thrombotic Thrombocytopenic Purpura | |
| Feb 11, 2005 | Von Willebrand Factor, Bleeding, and Thrombosis | |
| Feb 16, 2007 | Von Willebrand Factor, ADAMTS13, and the Regulation of Platelet Adhesion | |
| Feb 6, 2009 | Assembly and Destruction of Von Willebrand Factor | |
| Jan 13, 2012 | Von Willebrand Factor, ADAMTS13, and Thrombotic Microangiopathy | |
| Jan 18, 2013 | Assembly and Destruction of Von Willebrand Factor | |
| Jan 9, 2015 | Von Willebrand Factor, ADAMTS13 and Thrombotic Microangiopathy | |
| Saffitz, Jeff | Feb 27, 2004 | Mechanisms of Sudden Death in Cardiomyopathies Caused by Mutations in Cell-Cell Junction Proteins |
| Salvesen, Guy | Sep 24, 1993 | Inhibition of IL-1β Activation by a Virally Encoded Proteinase Inhibitor |
| Sands, Mark | Oct 29, 1993 | Molecular Characterization of the Genetic Defect and Modes of Treatment in Murine Mucopolysaccharidosis Type 7 |
| Nov 5, 1999 | Gene Therapy for Lysosomal Storage Diseases | |
| Apr 4, 2003 | Hematopoietic-Directed Therapies for Lysosomal Storage Diseases | |
| Mar 12, 2010 | Lysosomal Dysfunction Results in Altered Energy Balance | |
| Sanfilippo, Kristen | Feb 8, 2013 | Thrombosis in Myeloma |
| Feb 14, 2014 | Zoledronic Acid Versus Pamidronate in Patients with Multiple Myeloma: a Comparative Effectiveness Research Project | |
| Apr 21, 2016 | Statin Therapy Increases Survival in Myeloma | |
| Santoro, Sam | Mar 11, 1994 | Structure, Function and Regulation of the α2β1 Integrin |
| Feb 11, 2000 | Collagen Receptors: From Ligand Binding to Control of Cell Phenotype | |
| Sarma, Nayan | Feb 27, 2009 | Molecular Interactions of the Oncogene Nup98-HoxA9 |
| Saunders, Scott | Oct 7, 2005 | Heparan Sulfate Proteoglycans: Essential Modulators of Cellular Functions at the Plasma Membrane |
| Savage, Sharon | Nov 12, 2020 | The Growing Clinical and Genetic Spectrum of Telomere Biology Disorders |
| Schaffer, Jean | May 3, 2002 | Models and Mechanisms of Lipotoxicity |
| Schmid, Sandra | Oct 24, 2014 | 7th Rosalind Kornfeld Lecture: Dynamin: The Master Regulator of Clathrin-Mediated Endocytosis |
| Schreiber, Robert | May 15, 2014 | Stanley J. Korsmeyer Memorial Lecture: Cancer Immunoediting: Applying Mechanistic Insights to Cancer Immunotherapy |
| Schroeder, Mark | Apr 10, 2009 | Graft Versus Host Disease: a Novel Mouse Model and Therapy |
| Feb 4, 2011 | Exploring Cytokines to Treat Graft-vs-Host Disease | |
| Mar 2, 2012 | Mobilization of Allogeniec Sibling Peripheral Blood Stem Cell Donors with GM-CSF and Plerixafor – an Interim Analysis | |
| Searleman, Adam | Apr 1, 2011 | Determination of In Vivo Signaling Networks Governing Ductal Carcinoma In Situ Progression |
| Mar 16, 2012 | Characterization of a Mouse Model of Ductal Carcinoma In Situ of the Breast | |
| Feb 8, 2013 | Mechanisms of Transformation in HER2-Overexpressing Mammary Epithelium | |
| Semenkovich, Clay | May 17, 2002 | Fatty Acid Metabolism as a Mediator of Vascular Disease and Beta Cell Failure in Diabetes |
| Feb 24, 2012 | Lipogenesis: Much More Than Making Fat | |
| Semenza, Gregg | Oct 13, 2022 | Regulation of Erythropoiesis by Hypoxia-Inducible Factors |
| Oct 13, 2022 | 48th Annual Carl Moore Lecture: Regulation of Erythropoiesis by Hypoxia-Inducible Factors | |
| Sfeir, Agnel | Feb 22, 2018 | Protecting Our Genomes: Whenever, Wherever |
| Shafer, Jules | Nov 2, 1993 | Identification of Amino Acid Residues Important for the Heparin-Catalyzed Inactivation of Thrombin by Antithrombin III |
| Shah, Dhvanit | Feb 14, 2013 | Genetic Screen to Identify Genes Regulating Hematopoiesis |
| Shaw, Andrey | Feb 8, 2002 | Immunological Synapses and T Cell Signaling |
| Feb 10, 2006 | Macropinocytosis and Nephrotic Syndrome | |
| Sheehan, John | Mar 17, 1995 | Molecular Mechanism of Thrombin Regulation |
| Jun 3, 2019 | Plasma Factor IXa in Systemic Hypercoagulability | |
| Shen, Bo | Mar 2, 2021 | Novel Regulators of Bone Marrow Stem Cells: Growth and Mechanical Force |
| Sherr, Chuck | Nov 12, 2004 | 32nd Carl Moore Lecture: INK4a-ARF: A Marriage of Tumor Suppressors |
| Shim, Kyuhwan | Apr 1, 2005 | Work-in-Progress |
| Nov 10, 2006 | Platelet-VWF Complexes are Preferred Substrates of ADAMTS13 Under Fluid Shear Stress | |
| Oct 12, 2007 | Platelet-von Willebrand Factor Complexes Are Preferred Substrates of ADAMTS13 Under Fluid Shear Stress | |
| Shivdasani, Ramesh | Sep 15, 1995 | Transcriptional Control of Cell Fate Determination and Differentiation in Hematopoiesis: Lessons From Knockout Mice |
| Shulman, Gerald | Nov 6, 2009 | 37th Carl Moore Lecture: Cellular Mechanisms of Insulin Resistance: Implications for Obesity, Lipodystrophy, Metabolic Syndrome and Type 2 Diabetes |
| Signer, Robert | May 18, 2023 | Stem Cell Fitness and Longevity: The Role of Proteostasis |
| Silberstein, Lev | Apr 10, 2023 | Keeping Stem Cells Dormnant |
| Simon, Celeste | Nov 18, 1994 | Analysis of Hematopoiesis From the Study of Mutant Mice |
| Sly, Bill | Jun 5, 1998 | Mutations in HFE Protein Cause Hemochromatosis |
| Jan 27, 2006 | Functional Genomics of Carbonic Anhydrases: From Osteopetrosis to Protein Folding Diseases | |
| Snyder, Steve | Mar 10, 2016 | Mechanisms of Dysregulated Signaling in Mouse Models of Myeloproliferative Neoplasms |
| Oct 27, 2016 | The Role of NFκB in MPN Mouse Models | |
| Nov 16, 2017 | Exploring the Role of NFκB in PMN Mouse Models | |
| Soares, Barbara | May 26, 2022 | DNMT3A as a Novel Regulator of Telomerase in Human Stem Cells |
| May 11, 2023 | Impact of DNMT3A on Telomere Regulation in Human Cells | |
| Sood Gupta, Deepti | Jan 17, 2019 | A Novel SPIC/BCLAF1 Complex Reprograms PU.1 Activity in Pre-B Cells With Rag-Mediated DNA Breaks |
| Stamatoyannopoulos, John | Oct 14, 2016 | 44th Carl Moore Lecture: Decoding the Human Regulatory Genome |
| Stanley, Sam | Oct 15, 1999 | Pathways for Amebic Induction of Inflammation and Programmed Cell Death |
| Steet, Rich | Nov 19, 2004 | COG7 Deficiency: a Novel Congenital Disorder of Glycosylation |
| May 13, 2005 | Work-in-Progress | |
| Jan 6, 2006 | Work-in-Progress | |
| Steitz, Joan | Oct 30, 2009 | 2nd Rosalind Kornfeld Lecture: Regulating the Activity of MicroRNAs in Vertebrate Cells |
| Stenson, Bill | Sep 2, 2005 | Prostaglandins and the Epithelial Response to Radiation Injury |
| Stewart, Sheila | Mar 24, 2006 | The Yin and Yang of Cellular Senescence |
| Stoddard, Barry | Oct 17, 2006 | The Structure of Human Factor VIII and Its Inhibition Via Mutations, Antibodies, and Small Molecules |
| Storch, Greg | Mar 7, 2014 | Virologic, Genomic, and Transcriptomic Analysis of Fever Without a Source in Young Children |
| Sturgeon, Chris | Apr 11, 2013 | Modeling Developmental Hematopoiesis Using Pluripotent Stem Cells |
| Feb 20, 2015 | Modeling Developmental Hematopoiesis Using Pluripotent Stem Cells | |
| Sullivan, Ryan | Sep 30, 2011 | MicroRNA Deficient Natural Killer Cells Exhibit Decreased Survival but Enhanced Cytokine Production and Degranulation Capacity |
| Sep 28, 2012 | The Role of miR-155 in Natural Killer Cell Function | |
| Sep 20, 2013 | MiR-15/16 Antagonizes Myb to Control Natural Killer Cell Differentiation and Maturation | |
| Sykes, David | Feb 6, 2017 | “Curing by Maturing” – Developing Differentiation Therapy for the Treatment of Patients with Acute Myeloid Leukemia |
| Speaker | Date | Title |
|---|---|---|
| Tamai, Minori | Apr 25, 2019 | Modeling Infant Leukemia With Human Pluripotent Stem Cells |
| Taniguchi, Naoyuki | Sep 12, 1994 | Transfection of N-Acetylglucosaminyltransferase III Gene Into Melanomas Suppresses Lung Metastasis |
| Tarnawsky, Stefan | Feb 16, 2023 | Fitness of U2AF1-Mutant Clones |
| Tarr, Phil | Sep 29, 2006 | Escherichia Coli O157:H7 and the Hemolytic Uremic Syndrome: Host and Microbial Aspects |
| Taylor, James | Jan 15, 2016 | Epidemiologic and Mechanistic Insights into Risk Factors for Death in Adults with Sickle Cell Anemia |
| Teitelbaum, Steve | Sep 14, 2001 | RANK Ligand and Bone Cells |
| Thomas, Matt | Jan 23, 1998 | The Regulation of Adhesion and Signal Transduction by Protein Tyrosine Phosphatases |
| Thompson, Craig | Oct 20, 2006 | 34th Carl Moore Lecture: Programmed Cell Death: Apoptosis, Autophagy, and Necrosis |
| Tittiger, Mindy | May 11, 2007 | Parallels in Mucopolysaccharidosis (MPS) I and MPS 7 Aortic Disease |
| Tollefsen, Doug | Jan 24, 1997 | The Two Faces of Thrombin: Interactions of Exosites I and II With Inhibitors |
| Feb 12, 1999 | Allosteric Regulation of Thrombin by a Monoclonal Antibody That Binds to Exosite II | |
| Feb 9, 2001 | Function of Heparin Cofactor II in Vitro and in Vivo | |
| Apr 18, 2003 | Heparin Cofactor II and Thrombosis | |
| Feb 25, 2005 | Activation of Heparin Cofactor II by Vascular Glycosaminoglycans | |
| Jan 5, 2007 | Heparin Cofactor II Modulates the Response to Arterial Injury | |
| Mar 20, 2009 | TAP-Annexin V: a Novel Antithrombotic Agent | |
| Oct 22, 2010 | Activation of Heparin Cofactor II by Arterial Dermatan Sulfate | |
| Tomasson, Michael | Oct 12, 2001 | The Role of Fusion Oncogenes in the Multi-Step Pathogenesis of Acute Leukemia |
| Sep 21, 2007 | Genetic Progression Factors in Leukemia: One Good Mutation Deserves Another | |
| May 10, 2013 | The Role of Orphan SnoRNA ACA11 in the Pathogenesis of T(4;14)-Positive Multiple Myeloma | |
| Towler, Dwight | Mar 13, 1998 | Structure-Function Analysis of Msx2-Mediated Transcriptional Suppression: Promoter Repression Via RAP74 and the FGF Response Element DNA Binding Protein |
| Tran, David | Apr 1, 2011 | The Snail1-Twist1 Cooperation in EMT Maintenance and Cancer Dormancy |
| Traub, Linton | Oct 28, 1994 | Clathrin-Coated Vesicle Assembly on the Golgi |
| Jan 8, 1999 | Lysosomes, Liposomes and Synaptosomes: What Do They Teach Us About Clathrin-Coat Assembly? | |
| Trissal, Maria | May 13, 2011 | Role of Small Non-coding RNAs in Normal and Malignant Hematopoiesis |
| Apr 13, 2012 | Small Non Coding RNAs in Normal and Malignant Hematopoiesis | |
| Apr 5, 2013 | Dysregulation of the Imprinted DLK1-DIO3 Locus in Promyelocytic Leukemia | |
| Jan 17, 2014 | Dysregulation and Recurrent Mutation of miRNA-142 in Acute Myeloid Leukemia | |
| Trompouki, Eirini | Feb 7, 2013 | From Zebrafish to Man: BMP and Wnt Signaling Pathways in Normal and Stress Hematopoiesis |
| Tsai, Schickwann | Nov 10, 1995 | Developmental Control of Hematopoietic Stem Cells and Progenitors by Retinoic Acid Receptors |
| Tyagi, Garima Gupta | Mar 14, 2014 | Interactions Between VWF and ADAMTS13 (Catalytic and Non-catalytic) |
| Feb 11, 2016 | Single Molecule Analysis of Von Willebrand Factor Extension and Cleavage Using Magnetic Tweezers | |
| Jan 19, 2017 | Single Molecule Analysis of VWF Extension and Cleavage Using Magnetic Tweezers | |
| Mar 22, 2018 | Single Molecule Analysis of VWF Extension and Cleavage Using Magnetic Tweezers |
| Speaker | Date | Title |
|---|---|---|
| Ungewickell, Alex | Feb 18, 2005 | Work-in-Progress |
| Nov 18, 2005 | Work-in-Progress |
| Speaker | Date | Title |
|---|---|---|
| Vagelos, Roy | Sep 19, 2014 | Phil Majerus Symposium: Phil, Science, and Medicine |
| van Meel, Eline | Oct 14, 2011 | Discovery of the First Disease Causing Mutations in Methionyl-tRNA Synthetase (MARS) |
| Sep 14, 2012 | Mannose 6-Phosphate Independent Lysosomal Targeting of Acid alpha-Glucosidase | |
| Oct 25, 2013 | Mislocalization of Phosphotransferase as a Cause of Mucolipidosis III alpha/beta | |
| Oct 17, 2014 | Analysis of Mucolipidosis II/III GNPTAB Missense Mutations Identifies Domains of GlcNAc-1-Phosphotransferase Involved in Catalytic Function and Lysosomal Enzyme Recognition | |
| Van Tine, Brian | Jan 7, 2011 | Taspase1 and HER2+ Breast Cancer |
| Varki, Ajit | Oct 25, 2002 | Multiple Differences in Sialic Acid Biology Between Humans and Great Apes |
| May 6, 2005 | Selectins and Cancer: Mechanistic Connections and Therapeutic Implications | |
| Nov 18, 2011 | 39th Carl Moore Lecture: Adventures in Anthropogeny: From Sialic Acids to Human Uniqueness | |
| Varticovski, Lyuba | Oct 1, 1999 | Angiopoietins: Signal Transduction and Regulation of Endothelial Cell Biology |
| Verdoni, Angela | Dec 2, 2011 | Understanding the Role of DNA Methyltransferase 3A Mutations in Acute Myeloid Leukemia Pathogenesis |
| Oct 12, 2012 | Understanding the Role of DNMT3A Mutations in AML Pathogenesis | |
| Jan 17, 2014 | Understanding the Role of the DNMT3A R882H Mutation in AML Pathogenesis | |
| Vessoni, Alex | Jan 19, 2017 | Impact of Telomere Shortening on Mitochondria of Human Embryonic Stem Cells |
| Mar 15, 2018 | Investigating Cell Death and DNA Damage Response in hESCs With Short Telomeres | |
| Mar 28, 2019 | Telomere Dysfunction and Oncogene Stress Induces Differential Responses in Human Embryonic Stem Cells | |
| Sep 19, 2019 | DNA Damage Response in Human Embryonic Stem Cells With Short Telomeres | |
| Oct 22, 2020 | Investigating the Consequences of Telomere Dysfunction in Human Stem Cells | |
| Viatour, Patrick | Sep 15, 2016 | E2f Factors Integrate Cell Cycle and Non Cell Cycle Functions to Dictate Stem Cell Fate |
| Vicente, Cristina | Mar 4, 2005 | Work-in-Progress |
| Vindigni, Alessandro | Mar 9, 2017 | Mechanisms of Replication Stress Response to Chemotherapeutics |
| Virgin, Skip | Dec 12, 1997 | Interplay Between Herpesviruses and the Immune System |
| Apr 23, 2004 | Learning From Growth of an Ungrowable Virus | |
| Vomund, Tony | Jan 18, 2008 | The Interaction of ADAMTS13 and Endothelial Cells |
| Nov 14, 2008 | Characterizing the Interaction Between ADAMTS13 and Endothelial Cells |
| Speaker | Date | Title |
|---|---|---|
| Wagner, Julia | Feb 16, 2017 | CD56bright NK Cells Exhibit Potent Anti-Tumor Responses Following IL-15 Priming |
| Nov 16, 2017 | Impact of Inducible Eomes Deletion on the Murine NK Cell Compartment | |
| Feb 14, 2019 | A Novel NK Cell-Specific Inducible Cre Model Reveals a Critical Role for Eomes in the Survival, Homeostasis, and Function of Mature NK Cells | |
| Walter, Matt | Feb 23, 2007 | Myelodysplastic Syndrome and Deletions of Chromosome 5q31.2 |
| Wang, Beth | May 15, 2015 | Transcriptional Regulation of Human Primitive and Definitive Hematopoietic Progenitor Specification |
| Ward, Jeff | Apr 10, 2015 | High-Throughput Identification of Tumor Neoantigen-Specific Cytotoxic T-Cells |
| Feb 25, 2016 | Identification and Therapeutic Targeting of Tumor Specific Mutant Antigens | |
| Ward, Michael | Mar 4, 2005 | Work-in-Progress |
| Warner, Steve | Feb 1, 2008 | A Glance at the In Vivo Function of Rho GTPases Through the Fly Eye |
| Wartman, Lukas | Apr 29, 2005 | Work-in-Progress |
| Oct 1, 2010 | Conserved Progression Mutations in Mouse and Human Leukemia Genomes | |
| Weber, Jason | Nov 4, 2005 | Interpretation of Oncogenic Signals by the Nucleolus |
| Feb 22, 2008 | Regulating MRNA Translation Programs in Cancer | |
| Weilbaecher, Kathy | Nov 30, 2001 | The Role of Beta 3 Integrin in Metastasis |
| Oct 19, 2007 | CXCR4 Regulation of Osteoclast Development and Tumor Osteolysis | |
| Feb 26, 2010 | Hedgehog Signaling in Osteoclasts and Bone Metastasis | |
| Mar 8, 2013 | Targeting Beta3 Integrin Pathway Genes to Treat Cancer | |
| Welch, John | Oct 5, 2012 | The Origin and Evolution of AML Mutations |
| Wente, Susan | Feb 17, 1995 | Nucleocytoplasmic Trafficking: Insights From Yeast Nuclear Pore Complex Mutants |
| Feb 23, 2001 | Nuclear Entry and Exit: the Rules and the Players | |
| Nov 2, 2012 | 5th Rosalind Kornfeld Lecture: Beyond the Pore: From Nuclear MRNA Export to Translation | |
| Wilson, Dave | Mar 28, 1997 | GATA-Binding Proteins and Cardiovascular Development |
| Sep 8, 2000 | Blood and Guts: Erythroid Transcription Factors and Endodermal Development | |
| Mar 15, 2013 | Adrenocortical Development and Tumorigenesis: the Saga of Rosie | |
| Wilson, Mo | May 4, 2001 | A Promiscuous Inositol Kinase |
| Sep 8, 2006 | What the Structure of an Inositol Kinase Tells Us About Its Function | |
| Sep 26, 2008 | Neural Tube Defects in Mice With Aberrant Inositol Metabolism | |
| Sep 24, 2010 | A Mouse Model Linking Aberrant Inositol Metabolism to Defects in Neural Development | |
| Sep 21, 2012 | ITPK1: an Inositol Kinase Linked to Neural Tube Defects | |
| Nov 7, 2014 | The Many Roles of ITPK1, an Inositol Kinase | |
| Witte, Owen | Dec 11, 1998 | 26th Carl Moore Lecture: Hematolymphoid Signal Transduction by Cytoplasmic Tyrosine Kinases |
| Wolf, Beni | Jan 22, 2002 | Evasion of Mitochondria-Dependent Apoptosis by Cancer Cells |
| Wong, Pamela | Oct 8, 2020 | The Role of T-box Transcription Factors Eomes and Tbet in Mature Human Natural Killer Cells |
| Wong, Terrence | Jan 25, 2013 | The Genetics of Therapy-related AML |
| Feb 28, 2014 | The Role of TP53 Mutations in the Origin and Evolution of Therapy-Related AML | |
| Oct 31, 2014 | The Role of Early TP53 Mutations in the Origin and Evolution of Therapy-Related AML | |
| Oct 1, 2015 | Non-Malignant Oligoclonal Hematopoiesis Commonly Follows Induction Chemotherapy for Adult De Novo AML | |
| Jan 18, 2018 | Clonal Evolution of Hematopoietic Stem Cells During Chemotherapy and Transplantation | |
| Wu, Gregory | Mar 17, 2016 | The Role of B Cell Antigen Presentation in a Murine Autoimmune Model of Multiple Sclerosis |
| Wu, Qingyu | Jan 27, 1995 | Studies of Thrombin: Mutagenesis and Gene Targeting |
| Speaker | Date | Title |
|---|---|---|
| Xia, Lijun | Sep 22, 2022 | Platelet CLEC-2 in Vascular Integrity and Thrombosis |
| Xu, Lingfei | Mar 18, 2005 | Work-in-Progress |
| Speaker | Date | Title |
|---|---|---|
| Yao, Juo-Chin Robin | Oct 7, 2021 | TGF-β Signaling in Stromal Cells Contributes to Myelofibrosis, but Not Niche Disruption, in MPNs Throught JNK Activation |
| Yien, Yvette | Feb 16, 2016 | Mitochondrial Transporters in Erythroid Heme Metabolism |
| Yokoyama, Wayne | May 16, 1997 | The Emerging Spectrum of NK Cell Receptors |
| Yoo, Andrew | Jan 24, 2014 | Control of Neuronal Subtype Specificity During MicroRNA-Mediated Neuronal Reprogramming |
| York, John | Jan 26, 2001 | Insights Into the Biology of Inositol Signaling |
| Oct 6, 2006 | Signaling Specificity: Inositol Polyphosphate Messengers Regulate Drosophila Development | |
| Sep 14, 2011 | Interdisciplinary Seminar Series: Inositol Phosphate Communication: Insights Into the Cell’s ‘iPhone’ | |
| Sep 19, 2014 | Phil Majerus Symposium: Insights into Inositol Phosphate Cellular Signaling Pathways | |
| Young, Andrew | Feb 3, 2022 | Spacial Characterization of Clonal Mutations in the Bone Marrow |
| Mar 30, 2023 | Pre-Leukemic KMT2A Rearrangements After Topoisomerase Inhibitor Therapy | |
| Young, Margaret | Feb 18, 2011 | Whole Genome Sequencing of Murine Induced Pluripotent Stem Cells |
| Sep 30, 2011 | Canonical and Non-canonical HOX Expression Patterns in Acute Myelogenous Leukemia | |
| Yu, Jeff | May 11, 2007 | Investigation of the Biological Function of the C-terminal Domains in ADAMTS13 |
| Yu, Zheyong | Feb 1, 2008 | Modulation of ADAMTS13 Activity by Free Amino Acids |
| Speaker | Date | Title |
|---|---|---|
| Zaher, Hani | Nov 3, 2016 | Insights Into the Role of the Ribosome During mRNA and Nascent-Protein Quality Control |
| Zaretsky, Jesse | Feb 23, 2023 | Single-Cell Analysis of Neoadjuvant Immunotherapy in Head and Neck Cancer |
| Zhang, Chunfen | Mar 27, 2009 | Identification of Lysine Acetylation Sites on Inositol 1,3,4-Trisphosphate 5/6-Kinase |
| Apr 23, 2010 | Lysine Acetylation of Inositol 1,3,4-Trisphosphate 5/6-kinase | |
| Apr 29, 2011 | Lysine Acetylation of Inositol 1,3,4-Trisphosphate 5/6-kinase | |
| Apr 13, 2012 | The role of Myotubularin-related Phosphatases MTMR8 and MTMR9 in the Control of Autophagy | |
| Zhang, Lijuan | Sep 23, 2005 | Heparan and Chondroitin Sulfate Glycosaminoglycans: a Journey From Structure to Function |
| Zhang, Lingbo | Mar 16, 2021 | Understanding and Targeting Hematopoietic Stem and Progenitor Cells |
| Zhan, Huichun | Aug 3, 2017 | The Hematopoietic Niche in Myeloproliferative Neoplasms |
| Zho, Jun | Jan 19, 2007 | The Role of Type I PIP2 4-phosphatase in Stress Signaling |
| Zhu, Jian | Mar 18, 2011 | Structural and Functional Study of ADAMTS13 |
| Mar 30, 2012 | Small-angle X-ray Scattering Studies of ADAMTS13 Demonstrate a Conformational Response to Substrate Binding in Solution | |
| Mar 22, 2013 | Regulation of ADAMTS13 Activity | |
| May 9, 2014 | Structural Studies of ADAMTS13 Using Small-angle X-ray Scattering | |
| May 8, 2015 | A Folded ADAMTS13 Conformation Identified by SAXS Can Account for Allosteric Regulation by Distal TSP and CUB Domains | |
| Mar 10, 2016 | Study of Allosteric Regulation of ADAMTS13 by Small-Angle X-Ray Scattering | |
| Feb 2, 2017 | The Hunt for the “Minimal” Structure of a Functional ADAMTS13 by Small-Angle X-Ray Scattering | |
| Jan 11, 2018 | Structural and Functional Studies of ADAMTS13: AUC, HDX, and EM | |
| Zimmerman, Megan | Dec 13, 2018 | MDM2 Inhibition in T-Cell Acute Lymphoblastic Leukemia |
| Zou, Jun | Nov 9, 2007 | Type I Phosphatidylinositol-4,5-bisphosphate 4-phosphatase Regulates Stress-induced Apoptosis |
| Jan 16, 2009 | MTMR9 Increases MTMR6 Enzyme Activity, Stability, and Has a Role in Apoptosis | |
| Apr 23, 2010 | Characterization of Myotubularin Related Protein 8 | |
| Zutter, Mary | Feb 14, 2003 | The α2β1-Integrin Deficient Mouse: Defective Platelet and Mast Cell Function |