Jaehyung (Gus) Cho, PhD
Professor
- Phone: 314-362-8804
- Fax: 314-362-8826
- Email: jaehyung.cho@nospam.wustl.edu
Address:
- Division of Hematology
Mail Stop 8125-0020-08, Washington University, 660 South Euclid Avenue, St. Louis, MO 63110 (mail) - Room 8804A, Clinical Sciences Research Building (office)
- Room 8804/8808, Clinical Sciences Research Building (lab)
Research Interest: Platelet; Neutrophil; Thrombosis; Inflammation; Intravital microscopy
Research: The fundamental question that drives our research is, “How are thrombosis and inflammation intertwined?” Our current and future studies focus on understanding the mechanism mediating intravascular cell-cell interactions and vascular occlusion under thromboinflammatory conditions, including thrombosis, ischemia/reperfusion injury, and sickle cell disease.
For more information, please see Cho Lab
Biosketch
Education
- 2009-2006: Postdoctoral Fellow, Division of Hemostasis & Thrombosis, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA
- 2006-2001: PhD, Molecular & Cellular Pharmacology, University of Wisconsin, Madison, WI
- 1996-1990: BS/MS, Pharmacy (Pharmacology), ChungAng University, Seoul, South Korea
Academic Positions & Employment
- 2020-present: Professor, Departments of Medicine and Pathology & Immunology, Washington University School of Medicine (WUSM), St. Louis, MO
- 2020: Professor, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL
- 2020-2015: Associate Professor, Department of Pharmacology, University of Illinois at Chicago, Chicago, IL
- 2015-2009: Assistant Professor, Department of Pharmacology, University of Illinois at Chicago (UIC), Chicago, IL
- 2001-1996: Research Scientist, C&C Research Laboratories, Kyunggi-do, South Korea
University Appointments & Committees
- 2020-present: Member, Center for Cardiovascular Research
- 2020-present: Member, The Hope Center for Neurological Disorders
- 2020-present: Member, Division of Biology and Biomedical Sciences (Programs of Molecular Cell Biology and Immunology)
- 2020-present: Member, Institute of Clinical and Translational Sciences
- 2020-present: Associate Member, Siteman Cancer Center
- 2020-present: Admissions Committee of Molecular Cell Biology Program, WUSM
- 2016-present: Interviewer for MD students, UIC
- 2020-2014: Interviewer for MD/PhD students, UIC
- 2019-2014: Co-Director of Graduate Studies, Department of Pharmacology, UIC
- 2014-2012: Graduate Admissions Committee, Department of Pharmacology, UIC
Honors & Awards
- 2019: Department Faculty of the Year, UIC College of Medicine, Chicago, IL
- 2015: Rising Star Award, UIC College of Medicine, Chicago, IL
- 2014: Fellow of the American Heart Association
- 2014: Irvine H. Page Young Investigator Research Award, Finalist, Toronto, Canada
- 2012: Kenneth M. Brinkhous Young Investigator Award in Thrombosis, Finalist, Chicago, IL
- 2011: U.S. New Investigator Scholar Award, The XXIII International Society on Thrombosis and Haemostasis Congress, Kyoto, Japan
- 2009: Young Investigator Award, 4th Annual Platelet Colloquium, Washington, DC
- 2007: Young Investigator Best Article Award in Journal of Thrombosis and Haemostasis, The XXI International Society on Thrombosis and Haemostasis Congress, Geneva, Switzerland
Editorial Responsibilities
- 2022-present: Editorial Board, Antioxidants
- 2017-present: Editorial Board, Frontiers in Medicine
National/International Panels & Committees
- 2022: Ad-hoc Reviewer, NIH Special Emphasis Panel ZRG1 VH-C (02)
- 2022: External Reviewer, UK Research & Innovation (Biotechnology & Biological Sciences Research Council) Grant
- 2021: Ad-hoc Reviewer, NSF Graduate Research Fellowship Program (GRFP)
- 2021: Ad-hoc Reviewer, NIH Innate Immunity and Inflammation (III) Study Section
- 2021: Ad-hoc Reviewer, NIH Special Emphasis Panel, ZRG1 VH-N (02)
- 2021: Ad-hoc Reviewer, National Science Centre, Poland
- 2021: Ad-hoc Reviewer, NIH Hemostasis, Thrombosis, Blood Cells, and Transfusion (HTBT) Study Section
- 2021: Ad-hoc Reviewer, Peer Reviewed Medical Research Program (PRMRP) Discovery Viral Infectious Disease (DIS-VID-3) Study Section
- 2021: Ad-hoc Reviewer, Biotechnology and Biosciences Research Council, UKRI, UK
- 2021: Ad-hoc Reviewer, NIH Hemostasis, Thrombosis, Blood Cells, and Transfusion (HTBT) Study Section
- 2021: Ad-hoc Reviewer, NIH Director’s New Innovator Award Program (DP2) Study Section
- 2021: Ad-hoc Reviewer, NIH Special Emphasis Panel for Small Business Innovation Research
- 2020: Ad-hoc Reviewer, The Department of Defense Congressionally Directed Medical Research Programs (CDMRP) Respiratory Health and Effects Study Section
- 2020: Ad-hoc Reviewer, Chicago Biomedical Consortium (CBC) Accelerator Award
- 2020: External Reviewer, Austrian Science Fund (FWF) Hertha Firnberg Program, Austria
- 2020: The Clinical Research Training Center’s KL2 Career Development Program, WUSM
- 2020: Ad-hoc Reviewer, NIH Special Emphasis Panel, ZHL1 CSR-O (F1)
- 2020: Peer Review Committee, AHA Innovative Project Award Vascular Basic Sciences
- 2020-2015: National Science Foundation (NSF) Graduate Research Fellowship Program Committee
- 2018: Ad-hoc Reviewer, NIH Special Emphasis Panel, ZRG1 VH-J (02)
- 2018: Ad-hoc Reviewer, The Academy of Medical Sciences Newton International Fellowships, UK
- 2018-2017: Ad-hoc Reviewer, NIH, Physiology & Pathobiology of Cardiovascular and Respiratory Systems (F10A) Study Section
- 2018-2015: External Reviewer, Medical Research Council (MRC) Program, UK
- 2018-2012: Peer Review Committee, AHA Thrombosis Basic Research Study Section
- 2017: Ad-hoc Reviewer, NIH Molecular and Cellular Hematology (MCH) Study Section
- 2017: External Reviewer, Fondazione Telethon Research Program, Italy
- 2014: External Reviewer, Human Frontier Science Program (HFSP) Career Development Award, France
- 2012-2011: Peer Review Committee, American Heart Association (AHA), National Center and Midwest Affiliate Vascular Wall Biology Study Section
Professional Societies & Organizations
- 2017-present: Society for Redox Biology and Medicine
- 2017-present: North American Vascular Biology Organization
- 2016-present: American Association for the Advancement of Science
- 2015-present: North American Society on Thrombosis and Hemostasis
- 2010-present: American Heart Association
- 2008-present: American Society of Hematology
- 2006-present: International Society on Thrombosis and Haemostasis
Selected Publications
- A critical role for ERO1α in arterial thrombosis and ischemic stroke
Jha V, Xiong B, Kumari T, Kim K, Wang J, Lee J, Brown G, Asquith N, Gallagher J, Asherman L, Lambert T, Bai Y, Du X, Min JK, Sah R, Razani B, Lee JM, Italiano JE, Cho J
Circ Res 2023;132(11):e206-e222
- Neutrophil DREAM promotes neutrophil recruitment in vascular inflammation
Li J, Kumari T, Barazia A, Jha V, Jeong S, Olson A, Kim M, Lee BK, Manickam V, Song Z, Clemens R, Razani B, Kim J, Dinauer M, Cho J
J Exp Med. 2022: 219(1):e20211083 (Commentary in J Exp Med 2022:219:e20212141)
- Platelet protein disulfide isomerase promotes glycoprotein Ibα-mediated platelet-neutrophil interactions under thromboinflammatory conditions
Li J, Kim K, Jeong SY, Chiu J, Xiong B, Petukhov PA, Dai X, Li X, Andrews RK, Du X, Hogg PJ, Cho J
Circulation 2019;139(10):1300-1319
- Neutrophil AKT2 regulates heterotypic cell-cell interactions during vascular inflammation
Li J, Kim K, Hahm E, Molokie R, Hay N, Gordeuk VR, Du X, Cho J
J Clin Invest 2014;124:1483-1496 (Commentary in J Clin Invest 2014;124:1462-1465)
- Extracellular protein disulfide isomerase regulates ligand binding activity of αMβ2 integrin and neutrophil recruitment during vascular inflammation
Hahm E, Li J, Kim K, Huh S, Rogelj S, Cho J
Blood 2013;121:3789-3800 (Plenary Paper) (Commentary in Blood 2013;121:3779-3780)